Gut microbiota–generated metabolites in animal health and disease
WJ Lee, K Hase - Nature chemical biology, 2014 - nature.com
Gut microbiota is found in virtually any metazoan, from invertebrates to vertebrates. It has
long been believed that gut microbiota, more specifically, the activity of the microbiome and …
long been believed that gut microbiota, more specifically, the activity of the microbiome and …
[HTML][HTML] Metformin–A future therapy for neurodegenerative diseases: Theme: Drug discovery, development and delivery in Alzheimer's disease Guest Editor: Davide …
M Markowicz-Piasecka, J Sikora, A Szydłowska… - Pharmaceutical …, 2017 - Springer
Type 2 diabetes mellitus (T2DM) is a complex, chronic and progressive metabolic disease,
which is characterized by relative insulin deficiency, insulin resistance, and high glucose …
which is characterized by relative insulin deficiency, insulin resistance, and high glucose …
[HTML][HTML] Effects of berberine and metformin on intestinal inflammation and gut microbiome composition in db/db mice
W Zhang, JH Xu, T Yu, QK Chen - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Berberine and metformin, both established pharmaceutical agents with herbal origins, have
incidental beneficial effects on multiple diseases, including diabetes. These effects have …
incidental beneficial effects on multiple diseases, including diabetes. These effects have …
Neutrophil extracellular trap mitochondrial DNA and its autoantibody in systemic lupus erythematosus and a proof‐of‐concept trial of metformin
H Wang, T Li, S Chen, Y Gu, S Ye - Arthritis & rheumatology, 2015 - Wiley Online Library
Objective Neutrophil extracellular traps (NETs) have been shown to play an important role in
systemic lupus erythematosus (SLE) pathogenesis by activating plasmacytoid dendritic cells …
systemic lupus erythematosus (SLE) pathogenesis by activating plasmacytoid dendritic cells …
Metformin: a hopeful promise in aging research
MG Novelle, A Ali, C Diéguez… - Cold Spring …, 2016 - perspectivesinmedicine.cshlp.org
Even though the inevitable process of aging by itself cannot be considered a disease, it is
directly linked to life span and is the driving force behind all age-related diseases. It is an …
directly linked to life span and is the driving force behind all age-related diseases. It is an …
[HTML][HTML] Cancer and obesity: an obesity medicine association (OMA) clinical practice statement (CPS) 2022
E Lazarus, HE Bays - Obesity Pillars, 2022 - Elsevier
Abstract Background This Obesity Medicine Association (OMA) Clinical Practice Statement
(CPS) provides an overview of cancer and increased body fat. Methods The scientific …
(CPS) provides an overview of cancer and increased body fat. Methods The scientific …
[HTML][HTML] The impact of adipose tissue-derived factors on the hypothalamic-pituitary-gonadal (HPG) axis
C Tsatsanis, E Dermitzaki, P Avgoustinaki, N Malliaraki… - Hormones, 2015 - Springer
Adipose tissue produces factors, including adipokines, cytokines and chemokines which,
when released, systemically exert endocrine effects on multiple tissues thereby affecting …
when released, systemically exert endocrine effects on multiple tissues thereby affecting …
Is metformin a perfect drug? Updates in pharmacokinetics and pharmacodynamics
M Markowicz-Piasecka, KM Huttunen… - Current …, 2017 - ingentaconnect.com
Metformin, a synthetic biguanide, is currently one of the most frequently recommended
medications for type 2 diabetes treatment around the world. This review presents the latest …
medications for type 2 diabetes treatment around the world. This review presents the latest …
Natural compounds with anti-ageing activity
A Argyropoulou, N Aligiannis, IP Trougakos… - Natural product …, 2013 - pubs.rsc.org
Covering: up to the end of June 2013 Ageing is a complex molecular process driven by
diverse molecular pathways and biochemical events that are promoted by both …
diverse molecular pathways and biochemical events that are promoted by both …
Adsorption behavior of metformin drug on boron nitride fullerenes: Thermodynamics and DFT studies
AS Ghasemi, MR Taghartapeh, A Soltani… - Journal of Molecular …, 2019 - Elsevier
In this study, a density functional theory (DFT) calculation was carried out for the adsorption
behavior and detection of metformin on the exterior surfaces of pure and doped boron nitride …
behavior and detection of metformin on the exterior surfaces of pure and doped boron nitride …