[HTML][HTML] Bone loss at subchondral plate in knee osteoarthritis patients with hypertension and type 2 diabetes mellitus
Objectives This study aimed to characterize subchondral bone damages of knee
osteoarthritis (OA) patients in presence of the comorbidities, ie, hypertension and type 2 …
osteoarthritis (OA) patients in presence of the comorbidities, ie, hypertension and type 2 …
The future of osteoarthritis therapeutics: emerging biological therapy
A Mobasheri - Current rheumatology reports, 2013 - Springer
Biological therapy is a thriving area of research and development, and is well established for
chronic forms of rheumatoid arthritis (RA) and ankylosing spondylitis (AS). However, there is …
chronic forms of rheumatoid arthritis (RA) and ankylosing spondylitis (AS). However, there is …
Effects of genus Epimedium in the treatment of osteoarthritis and relevant signaling pathways
X Tong, Y Wang, B Dong, Y Li, S Lang, J Ma, X Ma - Chinese Medicine, 2023 - Springer
Osteoarthritis (OA) is a common chronic degenerative joint disease in clinical practice with a
high prevalence, especially in the elderly. Traditional Chinese Medicine (TCM) believes that …
high prevalence, especially in the elderly. Traditional Chinese Medicine (TCM) believes that …
A neutrophil cell membrane-biomimetic nanoplatform based on L-arginine nanoparticles for early osteoarthritis diagnosis and nitric oxide therapy
Q Yu, Y Huang, X Chen, Y Chen, X Zhu, Y Liu, J Liu - Nanoscale, 2022 - pubs.rsc.org
Osteoarthritis (OA) is a common debilitating disease affecting articular joints for which no
effective disease-modifying early diagnosis or medical therapy tools are currently available …
effective disease-modifying early diagnosis or medical therapy tools are currently available …
[HTML][HTML] Exploring the translational potential of clusterin as a biomarker of early osteoarthritis
U Kalvaityte, C Matta, E Bernotiene… - Journal of orthopaedic …, 2022 - Elsevier
Background Clusterin (CLU; also known as apolipoprotein J) is an ATP-independent
holdase chaperone that prevents proteotoxicity as a consequence of protein aggregation. It …
holdase chaperone that prevents proteotoxicity as a consequence of protein aggregation. It …
[HTML][HTML] The role of subchondral bone, and its histomorphology, on the dynamic viscoelasticity of cartilage, bone and osteochondral cores
Objective Viscoelastic properties of articular cartilage have been characterised at
physiological frequencies. However, studies investigating the interaction between cartilage …
physiological frequencies. However, studies investigating the interaction between cartilage …
Calcium phosphate mineralization through homogenous enzymatic catalysis: Investigation of the early stages
E Colaço, D Brouri, C Méthivier, L Valentin… - Journal of colloid and …, 2020 - Elsevier
Hypothesis The crystallization of calcium phosphate (CaP) is a ubiquitous process that
occurs in several mineralized tissues and involves a variety of biochemical and chemical …
occurs in several mineralized tissues and involves a variety of biochemical and chemical …
Tissue material properties and computational modelling of the human tibiofemoral joint: a critical review
Understanding how structural and functional alterations of individual tissues impact on
whole-joint function is challenging, particularly in humans where direct invasive …
whole-joint function is challenging, particularly in humans where direct invasive …
Expression of adipokines in osteoarthritis osteophytes and their effect on osteoblasts
S Junker, KW Frommer, G Krumbholz, L Tsiklauri… - Matrix Biology, 2017 - Elsevier
Objective Osteophyte formation in osteoarthritis (OA) is mediated by increased osteoblast
activity, which is-in turn-regulated by the Wnt signaling pathway. Obesity is regarded a risk …
activity, which is-in turn-regulated by the Wnt signaling pathway. Obesity is regarded a risk …
Cardiovascular drugs and osteoarthritis: effects of targeting ion channels
Osteoarthritis (OA) and cardiovascular diseases (CVD) share many similar features,
including similar risk factors and molecular mechanisms. A great number of cardiovascular …
including similar risk factors and molecular mechanisms. A great number of cardiovascular …