An adaptive drug-releasing contact lens for personalized treatment of ocular infections and injuries

R Sun, J Zhang, X Chen, Y Deng, J Gou, T Yin… - Journal of Controlled …, 2024 - Elsevier
This research introduces an innovative solution to address the challenges of bacterial
keratitis and alkali burns. Current treatments for bacterial keratitis and alkali burns rely on …

Therapeutic recommendations for the management of older adult patients with Sjögren's syndrome

S Retamozo, C Baldini, H Bootsma, S De Vita, T Dörner… - Drugs & Aging, 2021 - Springer
Primary Sjögren's syndrome (SjS) is a systemic autoimmune disease most commonly
diagnosed in middle-aged women. Although the disease can occur at all ages, it is …

Human corneal tissue model for nociceptive assessments

W Siran, CE Ghezzi, DM Cairns… - Advanced …, 2018 - Wiley Online Library
New in vitro tissue models to mimic in vivo conditions are needed to provide insight into
mechanisms involved in peripheral pain responses, potential therapeutic strategies to …

The management of neurotrophic keratitis

S Jabbour, C Ashton, S Balal, A Kaye… - Current opinion in …, 2021 - journals.lww.com
The management of neurotrophic keratitis : Current Opinion in Ophthalmology The
management of neurotrophic keratitis : Current Opinion in Ophthalmology Log in or Register …

The Royal College of Ophthalmologists guidelines on serum eye drops for the treatment of severe ocular surface disease: full report

S Rauz, SY Koay, B Foot, SB Kaye, F Figueiredo… - Eye, 2017 - nature.com
Ocular Surface Disease and the Tear Film Ocular surface disease (OSD) is a global public
health problem with significant impact on quality of life. The ocular surface is a specialised …

How to treat Sjögren's syndrome

EJ Price, AN Baer - Rheumatology, 2021 - academic.oup.com
SS is a chronic, autoimmune disease of unknown aetiology for which there is no known
curative treatment. Although dryness of the eyes and mouth are the classically described …

Efficacy of hyaluronic acid 0.3%, cyanocobalamin, electrolytes, and P-Plus in menopause patients with moderate dry eye disease

C De-Hita-Cantalejo, MC Sánchez-González… - Graefe's Archive for …, 2022 - Springer
Purpose To study the treatment efficacy of hyaluronic acid 0.3%, cyanocobalamin (vitamin
B12), electrolytes, and P-Plus in menopausal patients with moderate dry eye disease …

Distribution of polysulfide in human biological fluids and their association with amylase and sperm activities

M Ikeda, Y Ishima, VTG Chuang, M Sakai, H Osafune… - Molecules, 2019 - mdpi.com
Intracellular polysulfide could regulate the redox balance via its anti-oxidant activity.
However, the existence of polysulfide in biological fluids still remains unknown. Recently, we …

Bioengineered Lacrimal Gland Organ Regeneration in Vivo

M Hirayama, K Tsubota, T Tsuji - Journal of functional biomaterials, 2015 - mdpi.com
The lacrimal gland plays an important role in maintaining a homeostatic environment for
healthy ocular surfaces via tear secretion. Dry eye disease, which is caused by lacrimal …

Reversible HER2 antibody-drug conjugate–induced ocular toxicity

A Sharma, KM Riaz, MS Gill, A Patnaik… - Canadian Journal of …, 2022 - Elsevier
Purpose To report 3 cases of reversible epitheliopathy induced by A166—a human
epidermal growth factor receptor (HER2)-targeted antibody-drug conjugate (ADC) therapy …