Ubiquitin ligases: structure, function, and regulation

N Zheng, N Shabek - Annual review of biochemistry, 2017 - annualreviews.org
Ubiquitin E3 ligases control every aspect of eukaryotic biology by promoting protein
ubiquitination and degradation. At the end of a three-enzyme cascade, ubiquitin ligases …

Phytohormones as integrators of environmental signals in the regulation of mycorrhizal symbioses

MJ Pozo, JA López‐Ráez, C Azcón‐Aguilar… - New …, 2015 - Wiley Online Library
For survival, plants have to efficiently adjust their phenotype to environmental challenges,
finely coordinating their responses to balance growth and defence. Such phenotypic …

RCSB Protein Data Bank: Enabling biomedical research and drug discovery

DS Goodsell, C Zardecki, L Di Costanzo… - Protein …, 2020 - Wiley Online Library
Analyses of publicly available structural data reveal interesting insights into the impact of the
three‐dimensional (3D) structures of protein targets important for discovery of new drugs …

Behind the lines–actions of bacterial type III effector proteins in plant cells

D Büttner - FEMS microbiology reviews, 2016 - academic.oup.com
Pathogenicity of most Gram-negative plant-pathogenic bacteria depends on the type III
secretion (T3S) system, which translocates bacterial effector proteins into plant cells. Type III …

Strigolactones in plant interactions with beneficial and detrimental organisms: the Yin and Yang

JA López-Ráez, K Shirasu, E Foo - Trends in plant science, 2017 - cell.com
Strigolactones (SLs) are plant hormones that have important roles as modulators of plant
development. They were originally described as ex planta signaling molecules in the …

A conformational switch in the SCF-D3/MAX2 ubiquitin ligase facilitates strigolactone signalling

L Tal, M Palayam, M Ron, A Young, A Britt, N Shabek - Nature Plants, 2022 - nature.com
Strigolactones (SLs) are a class of plant hormones that regulate numerous processes of
growth and development. SL perception and signal activation involves interaction between F …

The UBC27–AIRP3 ubiquitination complex modulates ABA signaling by promoting the degradation of ABI1 in Arabidopsis

W Pan, B Lin, X Yang, L Liu, R Xia… - Proceedings of the …, 2020 - National Acad Sciences
Abscisic acid (ABA) is the key phytohormone in plant drought tolerance and stress
adaptation. The clade A protein phosphatase 2Cs (PP2Cs) like ABI1 (ABA-INSENSITIVE 1) …

Orchestrating the proteome with post-translational modifications

SH Spoel - Journal of experimental botany, 2018 - academic.oup.com
4500| Special Issue Editorial fixed, dynamicity in proteome outputs is critical for responding
rapidly and efficiently to emerging threats. Protein phosphorylation is arguably the best …

Hub protein controversy: taking a closer look at plant stress response hubs

K Vandereyken, J Van Leene, B De Coninck… - Frontiers in plant …, 2018 - frontiersin.org
Plant stress responses involve numerous changes at the molecular and cellular level and
are regulated by highly complex signaling pathways. Studying protein-protein interactions …

Ubiquitylation in plants: signaling hub for the integration of environmental signals

A Miricescu, K Goslin, E Graciet - Journal of Experimental Botany, 2018 - academic.oup.com
A fundamental question in biology is how organisms integrate the plethora of environmental
cues that they perceive to trigger a co-ordinated response. The regulation of protein stability …