Cardiovascular disease (CVD) is one of the most severe diseases in clinics. Fibroblast
growth factor 21 (FGF21) is regarded as an important metabolic regulator playing a …

Zimmet P, Thomas CR (International Diabetes Institute, Caulfield, Australia; and BioScience
Communications, London). Genotype, obesity and cardiovascular disease–has technical …

KK/Snk mice (previously KK/San) possessing a recessive mutation (hypl) of the angiopoietin-
like 3 (Angptl3) gene homozygously exhibit a marked reduction of VLDL due to the …

The nuclear receptor peroxisome proliferator-activated receptor α (PPARα) is a key regulator
of genes implicated in lipid homeostasis and inflammation. PPARα trans-activity is …

Coronary artery calcification (CAC) is mainly associated with coronary atherosclerosis,
which is an indicator of coronary artery disease (CAD). CAC refers to the accumulation of …

Statins have revolutionized the treatment of hypercholesterolemia due to their ability to
inhibit cholesterol biosynthesis. Their immunomodulatory and anti-inflammatory effects and …

Objectives: Epidemiologic reports indicate that lipid-lowering agents (LLAs) protect against
dementia. We hypothesized that LLAs might affect cholinergic systems. The effects of LLAs …

Three series of N-acyl and N-cyclohexyl-or N-methyl or N-phenyl-thioureas of 4-substituted
(methyl, phenyl, 2-pyridyl) piperazines (4–12) were synthesised according to a highly …

Wzrost stężenia fibrynogenu oraz lepkości krwi i osocza towarzyszy wielu czynnikom ryzyka
miażdżycy, takim jak: cukrzyca, nadciśnienie tętnicze, otyłość, płeć męska, wiek, palenie …

The whole blood viscosity (WBV) is one of the major independent indicators for the risk of
cardiovascular disease, stroke, and peripheral arterial diseases. Furthermore, oxidized LDL …