The role of inflammation in the pathogenesis of preeclampsia
M Michalczyk, A Celewicz, M Celewicz… - Mediators of …, 2020 - Wiley Online Library
Preeclampsia (PE) affects 5‐8% of pregnant women, and it is the major cause of perinatal
morbidity and mortality. It is defined as arterial hypertension in women after 20 weeks of …
morbidity and mortality. It is defined as arterial hypertension in women after 20 weeks of …
Cellular immune responses in the pathophysiology of preeclampsia
Preeclampsia, defined as new-onset hypertension accompanied by proteinuria occurring at
20 weeks of gestation or later, is a leading cause of perinatal morbidity and mortality …
20 weeks of gestation or later, is a leading cause of perinatal morbidity and mortality …
Gut dysbiosis induces the development of pre-eclampsia through bacterial translocation
Objective Pre-eclampsia (PE) is one of the malignant metabolic diseases that complicate
pregnancy. Gut dysbiosis has been identified for causing metabolic diseases, but the role of …
pregnancy. Gut dysbiosis has been identified for causing metabolic diseases, but the role of …
Maternal immune responses and obstetrical outcomes of pregnant women with COVID-19 and possible health risks of offspring
Abstract Coronavirus disease 2019 (COVID-19) pandemic has spread rapidly across the
world. The vast majority of patients with COVID-19 manifest mild to moderate symptoms but …
world. The vast majority of patients with COVID-19 manifest mild to moderate symptoms but …
Role of the NLRP3 inflammasome in preeclampsia
K Shirasuna, T Karasawa, M Takahashi - Frontiers in endocrinology, 2020 - frontiersin.org
Reproduction involves tightly regulated series of events and the immune system is involved
in an array of reproductive processes. Disruption of well-controlled immune functions leads …
in an array of reproductive processes. Disruption of well-controlled immune functions leads …
Role of the monocyte–macrophage system in normal pregnancy and preeclampsia
The proper functioning of the monocyte–macrophage system, an important unit of innate
immunity, ensures the normal course of pregnancy. In this review, we present the current …
immunity, ensures the normal course of pregnancy. In this review, we present the current …
Doxorubicin induced immune abnormalities and inflammatory responses via HMGB1, HIF1-α and VEGF pathway in progressive of cardiovascular damage
Background: Doxorubicin (DOX) is a commonly used treatment for cancer and the
mechanism of DOX-induced cardiomyocyte damage in cardiovascular disease is not fully …
mechanism of DOX-induced cardiomyocyte damage in cardiovascular disease is not fully …
MicroRNAs: small molecules with a large impact on pre‐eclampsia
M Hemmatzadeh, N Shomali… - Journal of cellular …, 2020 - Wiley Online Library
As critical mediators in biological processes, microRNAs (miRNAs) which are small and
endogenous noncoding RNAs have been associated with disease progression, cell …
endogenous noncoding RNAs have been associated with disease progression, cell …
Gut microbiota changes in preeclampsia, abnormal placental growth and healthy pregnant women
L Huang, M Cai, L Li, X Zhang, Y Xu, J Xiao, Q Huang… - BMC microbiology, 2021 - Springer
Background Preeclampsia (PE) is a condition of high blood pressure that is usually
concurrent with proteinuria in pregnancy. PE complicates the management of both maternal …
concurrent with proteinuria in pregnancy. PE complicates the management of both maternal …
Preeclamptic women have decreased circulating IL-10 (Interleukin-10) values at the time of preeclampsia diagnosis: systematic review and meta-analysis
A key immunomodulatory cytokine, IL-10 (interleukin-10), has been shown to be
dysregulated in preeclampsia, a pregnancy-specific hypertensive disorder, further …
dysregulated in preeclampsia, a pregnancy-specific hypertensive disorder, further …