Circadian regulation of glucose, lipid, and energy metabolism in humans
E Poggiogalle, H Jamshed, CM Peterson - Metabolism, 2018 - Elsevier
The circadian system orchestrates metabolism in daily 24-hour cycles. Such rhythms
organize metabolism by temporally separating opposing metabolic processes and by …
organize metabolism by temporally separating opposing metabolic processes and by …
The functional and clinical significance of the 24-hour rhythm of circulating glucocorticoids
Adrenal glucocorticoids are major modulators of multiple functions, including energy
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …
Circadian misalignment augments markers of insulin resistance and inflammation, independently of sleep loss
R Leproult, U Holmbäck, E Van Cauter - Diabetes, 2014 - Am Diabetes Assoc
Shift workers, who are exposed to irregular sleep schedules resulting in sleep deprivation
and misalignment of circadian rhythms, have an increased risk of diabetes relative to day …
and misalignment of circadian rhythms, have an increased risk of diabetes relative to day …
Tissue-specific clocks in Arabidopsis show asymmetric coupling
Many organisms rely on a circadian clock system to adapt to daily and seasonal
environmental changes. The mammalian circadian clock consists of a central clock in the …
environmental changes. The mammalian circadian clock consists of a central clock in the …
[HTML][HTML] When rhythms meet the blues: circadian interactions with the microbiota-gut-brain axis
The microbiota-gut-brain axis encompasses a bidirectional mode of communication
between the microorganisms residing in our gut, and our brain function and behavior. The …
between the microorganisms residing in our gut, and our brain function and behavior. The …
Loss of circadian clock gene expression is associated with tumor progression in breast cancer
C Cadenas, L Van De Sandt, K Edlund, M Lohr… - Cell Cycle, 2014 - Taylor & Francis
Several studies suggest a link between circadian rhythm disturbances and tumorigenesis.
However, the association between circadian clock genes and prognosis in breast cancer …
However, the association between circadian clock genes and prognosis in breast cancer …
Crosstalk between the circadian clock circuitry and the immune system
N Cermakian, T Lange, D Golombek… - Chronobiology …, 2013 - Taylor & Francis
Various features, components, and functions of the immune system present daily variations.
Immunocompetent cell counts and cytokine levels present variations according to the time of …
Immunocompetent cell counts and cytokine levels present variations according to the time of …
The circadian clock in cancer development and therapy
L Fu, NM Kettner - Progress in molecular biology and translational …, 2013 - Elsevier
Most aspects of mammalian function display circadian rhythms driven by an endogenous
clock. The circadian clock is operated by genes and comprises a central clock in the brain …
clock. The circadian clock is operated by genes and comprises a central clock in the brain …
How sleep and wakefulness influence circadian rhythmicity: effects of insufficient and mistimed sleep on the animal and human transcriptome
The mammalian circadian system is a multi‐oscillator, hierarchically organised system
where a central pacemaker synchronises behavioural, physiological and gene expression …
where a central pacemaker synchronises behavioural, physiological and gene expression …
Circadian depression: a mood disorder phenotype
Major mood syndromes are among the most common and disabling mental disorders.
However, a lack of clear delineation of their underlying pathophysiological mechanisms is a …
However, a lack of clear delineation of their underlying pathophysiological mechanisms is a …