Sex differences in vulnerability to addiction

JA Quigley, MK Logsdon, CA Turner, IL Gonzalez… - …, 2021 - Elsevier
This article reviews evidence for sex differences in vulnerability to addiction with an
emphasis on the neural mechanisms underlying these differences. Sex differences in the …

Regulation of sex differences in risk-based decision making by gonadal hormones: insights from rodent models

CA Orsini, LM Truckenbrod, AR Wheeler - Behavioural processes, 2022 - Elsevier
Men and women differ in their ability to evaluate options that vary in their rewards and the
risks that are associated with these outcomes. Most studies have shown that women are …

Neural mechanisms mediating sex differences in motivation for reward: cognitive bias, food, gambling, and drugs of abuse

CA Orsini, TE Brown, TE Hodges… - Journal of …, 2022 - Soc Neuroscience
Sex differences in motivation for food rewards, gambling, and drugs of abuse are modulated
by multiple factors, including sensory stimuli, gonadal hormones, and cognitive bias. Cues …

[HTML][HTML] Sex differences in neural substrates of risk taking: Implications for sex-specific vulnerabilities to internet gaming disorder

L Wang, H Zheng, M Wang, S Chen, X Du… - Journal of Behavioral …, 2022 - akjournals.com
Background and aims Sex differences in internet gaming disorder (IGD) remain unknown.
Investigating sex-specific neural features that underlie the core risk factor (ie, risk-taking) of …

Effects of fentanyl self-administration on risk-taking behavior in male rats

AR Wheeler, LM Truckenbrod, EM Cooper… - …, 2023 - Springer
Rationale Individuals with opioid use disorder (OUD) exhibit impaired decision making and
elevated risk-taking behavior. In contrast to the effects of natural and semi-synthetic opioids …

Cognitive mechanisms underlying decision making involving risk of explicit punishment in male and female rats

LM Truckenbrod, EM Cooper, CA Orsini - Cognitive, Affective, & Behavioral …, 2023 - Springer
Individuals engage in the process of risk-based decision making on a daily basis to navigate
various aspects of life. There are, however, individual differences in this form of decision …

Chronic cocaine causes age-dependent increases in risky choice in both males and females.

SL Blaes, KG Shimp, SM Betzhold, B Setlow… - Behavioral …, 2022 - psycnet.apa.org
Individuals who use cocaine exhibit maladaptive decision-making, overweighting rewards,
and underweighting potential risks. We previously showed that chronic cocaine self …

Sex mechanisms as nonbinary influences on cognitive diversity

NM Grissom, N Glewwe, C Chen, E Giglio - Hormones and Behavior, 2024 - Elsevier
Essentially all neuropsychiatric diagnoses show some degree of sex and/or gender
differences in their etiology, diagnosis, or prognosis. As a result, the roles of sex-related …

Effects of reproductive experience on cost-benefit decision making in female rats

M Faraji, OA Viera-Resto, B Setlow… - Frontiers in Behavioral …, 2024 - frontiersin.org
Many individuals undergo mating and/or other aspects of reproductive experience at some
point in their lives, and pregnancy and childbirth in particular are associated with alterations …

Relative to females, male rats are more willing to forego obtaining sucrose reward in order to prevent harm to their cage mate

EM Hess, M Venniro, TD Gould - Psychopharmacology, 2023 - Springer
Rationale Empathy, or the ability to perceive, share, and act upon the emotions of another, is
a crucial social skill and is dysfunctional in autism and schizophrenia. While the complexities …