Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm and was the first
neoplastic disease associated with a well-defined genotypic anomaly―the presence of the …

Piper betle leaves are widely cultivated in Malaysia, India, Indonesia and Thailand. They
have been used as a traditional medicine for centuries due to their medicinal properties …

The black pepper, most commonly used in Indian cuisines for ages, is considered as “king of
spices.” The present study evaluates the anticancer potential of black pepper and its main …

Abstract Treatment-free remission (TFR) is one of the therapeutic goals for patients with
chronic phase chronic myeloid leukemia (CML-CP). Although previous reports indicated that …

Achievement of treatment-free remission (TFR) after tyrosine kinase inhibitor (TKI)
discontinuation in patients who show a durable deep molecular response (DMR) during TKI …

Tyrosine kinases inhibitors (TKIs) revolutionized chronic myeloid leukemia (CML) treatment
for many years, prolonging patients' life expectancy to be comparable to age-matched …

BCR-ABL1 tyrosine kinase inhibitors (TKIs) have dramatically improved survival outcomes in
patients with chronic phase chronic myeloid leukemia (CML-CP) and are associated with a …

Background Myeloid-derived suppressor cell (MDSC)-mediated immune suppression, and
natural killer (NK) and/or T cell-mediated immune responses play important roles in Chronic …

Severe acute respiratory syndrome (SARS) caused by a novel coronavirus-2 (CoV-2), also
known as COVID-19, has spread rapidly worldwide since it is recognized as a public health …

Background: Since late December 2019, the outbreak of the novel coronavirus disease,
COVID-19, that began in Wuhan, has become endemic in China and more than 100 …