Follicle-stimulating hormone signaling is essential for the initiation and early stages of
spermatogenesis. Follicle-stimulating hormone receptor is exclusively expressed in Sertoli …

Retinoic acid, an active metabolite of vitamin A, is necessary for many developmental
processes in mammals. Much of the field of reproduction has looked toward retinoic acid as …

Retinoic acid (RA) is the proposed mammalian 'meiosis inducing substance'. However,
evidence for this role comes from studies in the fetal ovary, where germ cell differentiation …

Control over gene expression is exerted, in multiple stages of spermatogenesis, at the post-
transcriptional level by RNA binding proteins (RBPs). We identify here an essential role in …

Simple Summary Due to the complexity of sperm cell reproduction and maturation, the
genetic structure of semen traits remains largely unknown. In our study, we used weighted …

Male meiosis is a complex process whereby spermatocytes undergo cell division to form
haploid cells. This review focuses on the role of retinoic acid (RA) in meiosis, as well as …

Sertoli cells are a critical component of the testis environment for their role in maintaining
seminiferous tubule structure, establishing the blood-testis barrier, and nourishing maturing …

The formation of spermatozoa starts with a germ-line stem cell creating a pool of progenitor
cells or undifferentiated spermatogonia. There is a requirement for these progenitor cells to …

In brief Mrhl lncRNA regulates the Wnt signaling pathway in mouse spermatogonial cells,
resulting in the commitment of B-type spermatogonia to meiotic entry through Mrhl lncRNA …

Spermatogenesis is a highly organized and regulated process that requires the constant
production of millions of gametes over the reproductive lifetime of the mammalian male. This …