Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …

Intracellular and extracellular interactions with proteins enables the functional and
mechanistic diversity of lipids. Fatty acid-binding proteins (FABPs) were originally described …

Oxidative stress contributes to the pathogenesis of acute lung injury. Protein S-
glutathionylation plays an important role in cellular antioxidant defense. Here we report that …

Despite growing interest and a recent surge in papers, the role of autophagy in glucose and
lipid metabolism is unclear. We produced mice with skeletal muscle–specific deletion of …

Triglycerides are exclusively transported with chylomicrons and this process is critically
dependent on MTP. In addition to chylomicrons, absorption of phospholipids, free …

Fatty acid-binding proteins (FABPs) are members of the intracellular lipid-binding protein
(iLBP) family and are involved in reversibly binding intracellular hydrophobic ligands and …

Colorectal carcinoma (CRC) is one of the most frequently diagnosed carcinomas and one of
the leading causes of cancer-related death worldwide. Metabolic reprogramming, a hallmark …

Intestinal lipid transport plays a central role in fat homeostasis. Here we review the pathways
regulating intestinal absorption and delivery of dietary and biliary lipid substrates, principally …

Long-chain fatty acyl-coenzyme As (CoAs) are critical regulatory molecules and metabolic
intermediates. The initial step in their synthesis is the activation of fatty acids by one of 13 …

In recent years, fatty acid binding protein 5 (FABP5), also known as fatty acid transporter,
has been widely researched with the help of modern genetic technology. Emerging …