An active targeting strategy-enabled DNA tetrahedron delivery vehicle could facilitate stable
drug encapsulation and stimuli-responsive on-demand release, building a universal …

Strategies for functionalizing diverse tetrahedral framework nucleic acids (tFNAs) have been
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …

DNA materials have emerged as potential nanocarriers for targeted cancer therapy to
precisely deliver cargos with specific purposes. The short half‐life and low bioavailability of …

Rapid and efficient tools for early cancer detection have diagnostic and therapeutic value.
Given that the DNA hairpin‐based hybridization chain reaction (HCR) is effective in …

The physicochemical nature of DNA allows the assembly of highly predictable structures via
several fabrication strategies, which have been applied to make breakthroughs in various …

Diabetic osteoporosis (DOP) is a significant complication that poses continuous threat to the
bone health of patients with diabetes; however, currently, there are no effective treatment …

Choroidal neovascularization (CNV) is a common pathological feature of various eye
diseases and an important cause of visual impairment in middle-aged and elderly patients …

Severe acute pancreatitis (SAP) is an inflammatory disease of the pancreas accompanied
by tissue injury and necrosis. It not only affects the pancreas but also triggers a systemic …

Infection of bone defects is a common clinical problem that negatively impacts bone repair
and may result in the development of antibiotic resistance due to the long-term use of …

MicroRNAs (miRs) play an important role in regulating gene expression. Limited by their
instabilities, miR therapeutics require delivery vehicles. Tetrahedral framework nucleic acids …