Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease–novel insights into cellular communication circuits
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease and is
emerging as the leading cause of cirrhosis, liver transplantation and hepatocellular …
emerging as the leading cause of cirrhosis, liver transplantation and hepatocellular …
[HTML][HTML] The bidirectional immune crosstalk in metabolic dysfunction-associated steatotic liver disease
K Sawada, H Chung, S Softic, ME Moreno-Fernandez… - Cell Metabolism, 2023 - cell.com
Metabolic dysfunction-associated steatotic liver disease (MASLD) is an unabated risk factor
for end-stage liver diseases with no available therapies. Dysregulated immune responses …
for end-stage liver diseases with no available therapies. Dysregulated immune responses …
[HTML][HTML] Hepatic stellate cell-immune interactions in NASH
JK Carter, SL Friedman - Frontiers in Endocrinology, 2022 - frontiersin.org
Nonalcoholic fatty liver disease (NAFLD) is the dominant cause of liver disease worldwide.
Nonalcoholic steatohepatitis (NASH), a more aggressive presentation of NAFLD, is …
Nonalcoholic steatohepatitis (NASH), a more aggressive presentation of NAFLD, is …
[HTML][HTML] Epidemiologic, genetic, pathogenic, metabolic, epigenetic aspects involved in NASH-HCC: current therapeutic strategies
J Gutiérrez-Cuevas, S Lucano-Landeros… - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is an aggressive human cancer and is
caused as consequences of chronic liver diseases. Although HCC is more common in …
caused as consequences of chronic liver diseases. Although HCC is more common in …
[HTML][HTML] Non-alcoholic fatty liver disease: Immunological mechanisms and current treatments
L Petagine, MG Zariwala, VB Patel - World Journal of …, 2023 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) causes significant global disease burden and is a
leading cause of mortality. NAFLD induces a myriad of aberrant changes in hepatocytes at …
leading cause of mortality. NAFLD induces a myriad of aberrant changes in hepatocytes at …
[HTML][HTML] The role of complement in nonalcoholic fatty liver disease
Z Guo, X Fan, J Yao, S Tomlinson, G Yuan… - Frontiers in …, 2022 - frontiersin.org
Nonalcoholic fatty liver disease (NAFLD) has become a leading cause of chronic liver
diseases globally. NAFLD includes a range of hepatic manifestations, starting with liver …
diseases globally. NAFLD includes a range of hepatic manifestations, starting with liver …
[HTML][HTML] Bidirectional association between psoriasis and nonalcoholic fatty liver disease: real-world evidence from two longitudinal cohort studies
Background Association between nonalcoholic fatty liver disease (NAFLD) and future
psoriasis has not yet been confirmed, although the two diseases partially share a common …
psoriasis has not yet been confirmed, although the two diseases partially share a common …
[HTML][HTML] MAIT cells in liver inflammation and fibrosis
H Mehta, MJ Lett, P Klenerman… - Seminars in …, 2022 - Springer
Mucosal-associated invariant T cells or MAIT cells are an abundant cell type in humans and
especially so in the liver. MAIT cells are a subset of T lymphocytes that sit at a bridge …
especially so in the liver. MAIT cells are a subset of T lymphocytes that sit at a bridge …
[HTML][HTML] Changes in m6A in steatotic liver disease
Fatty liver disease is one of the major causes of morbidity and mortality worldwide. Fatty liver
includes non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis …
includes non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis …
HILPDA promotes NASH-driven HCC development by restraining intracellular fatty acid flux in hypoxia
D Povero, Y Chen, SM Johnson, CE McMahon… - Journal of …, 2023 - Elsevier
Background & Aims The prevalence of non-alcoholic steatohepatitis (NASH)-driven
hepatocellular carcinoma (HCC) is rising rapidly, yet its underlying mechanisms remain …
hepatocellular carcinoma (HCC) is rising rapidly, yet its underlying mechanisms remain …