Objective: To determine our community's incidence of clinically suspected normal pressure
hydrocephalus (NPH), the rate of shunting for NPH, and short-and long-term outcomes of …

In this article, the role of hypothermia and neuroprotection for neonatal encephalopathy will
be discussed. The incidence of encephalopathy due to hypoxia ischemia as well as the …

Background: Microglia are key mediators of inflammation during perinatal brain injury. As
shown experimentally after inflammation-sensitized hypoxic ischemic (HI) brain injury …

Perinatal hypoxia-ischemia resulting in death or lifelong disabilities remains a major clinical
disorder. Neonatal models of hypoxia-ischemia in rodents have enhanced our …

Background and Purpose—Critical factors influencing the neuroprotective efficacy of
postischemic hypothermia include depth, duration, and time of onset of cooling. In clinical …

5,611,767 A 3/1997 Williams 5,713,923 A 2/1998 Ward et al..................... 607/3 5,716.377 A
2/1998 Rise et al. 5,735,814 A 4/1998 Elsberry et al............... 604/43 bundle to at least one …

Objective. To compare brain temperature and cerebral blood flow (CBF) during head and
body cooling, with and without systemic hypoxemia. Methods. Seventeen newborn swine …

Objective: Therapeutic hypothermia instituted within 6 h of birth has been shown to improve
neurodevelopmental outcomes in term newborns with moderate–to–severe hypoxic …

Severe hypoxic-ischemic encephalopathy (HIE) is a devastating condition that can lead to
mortality and long-term disabilities in term newborns. No rapid and reliable laboratory test …

Prolonged, moderate cerebral hypothermia is consistently neuroprotective after
experimental hypoxia–ischaemia; however, it has not been tested in the preterm brain …