Hypothermia may be an ideal neuroprotective intervention in hypoxic-ischemic
encephalopathy after perinatal asphyxia. The present study describes the long-term effects …

Recent evidence suggests that the current ILCOR guidelines regarding hypothermia for the
treatment of neonatal encephalopathy need urgent revision. In 2005 when the current …

Therapeutic hypothermia (TH) is now well established to improve intact survival after
neonatal encephalopathy (NE). However, many questions could not be addressed by the …

Postresuscitation cerebral hypothermia is consistently neuroprotective in experimental
preparations; however, its effects on white matter injury are poorly understood. Using a …

Moderate to severe hypoxic–ischemic injury in newborn infants, manifested as
encephalopathy immediately or within hours after birth, is associated with a high risk of …

Perinatal hypoxic-ischemic encephalopathy is a leading cause of neonatal death and
disability. Therapeutic hypothermia significantly reduces death and major disability …

OBJECTIVE. The goals were to identify predictor variables and to develop scoring systems
and classification trees to predict death/disability or death in infants with hypoxic-ischemic …

Significance: Hypoxic-ischemic events due to intrapartum complications represent the
second cause of neonatal mortality and initiate an acute brain disorder known as hypoxic …

Perinatal brain injury in the term infant is a relatively uncommon event. The principal lesions
are intracranial hemorrhage including subarachnoid, subdural, intraparenchymal …

Objectives To examine whether using an amplitude-integrated electroencephalography
(aEEG) severity pattern as an entry criterion for therapeutic hypothermia better selects …