Cerebral oedema is associated with morbidity and mortality after traumatic brain injury (TBI).
Noradrenaline levels are increased after TBI,–, and the amplitude of the increase in …

The newly discovered glymphatic system acts as pseudolymphatic vessels subserving brain
waste clearance and is functionally dependent on astrocytic aquaporin‐4 channels. The …

The brain's high bioenergetic state is paralleled by high metabolic waste production.
Authentic lymphatic vasculature is lacking in brain parenchyma. Cerebrospinal fluid (CSF) …

Abstract Background Critical closing pressure (CrCP) and resistance-area product (RAP)
have been conceived as compasses to optimize cerebral perfusion pressure (CPP) and …

Objective To evaluate the value of an adjuvant cisternostomy (AC) to decompressive
craniectomy (DC) for the management of patients with severe traumatic brain injury (sTBI) …

Background: Decompressive craniectomy (DC) is considered the gold standard blanket
surgical procedure for all medically intractable cerebral oedema in Traumatic Brain Injury …

Background The current surgical treatment of choice for refractory intracranial hypertension
after traumatic brain injury (TBI) is decompressive craniectomy. Despite efficacy in control of …

Addiction is a pressing social problem worldwide and opioid dependence can be
considered the strongest and most difficult addiction to treat. Mesolimbic and mesocortical …

Background: Spaceflight-associated neuro-ocular syndrome (SANS) was first described in
2011 and is associated with structural ocular changes found to occur in astronauts after long …

Background Hydrocephalus is one of the major complications of aneurysmal subarachnoid
haemorrhage (aSAH). In the acute setting, an external ventricular drain (EVD) is used for …