This volume covers all aspects of melanin pigmentation, providing a concise,
comprehensive picture of new knowledge gained at the frontiers of research. It draws …

A method for the quantitative analysis of eumelanin and pheomelanin in tissues, eg, hair
and melanoma, is described. The method is simple and rapid because it does not require …

Synthetic dopa melanin and cysteinyldopa melanin have different electron spin resonance
spectra. Data are reported for mixtures of these melanins and for dopa-cysteinyldopa …

In this study, a method is provided for analyzing quantitatively the content and the class of
melanin pigments in the tissues, eg, hair and melanoma. The method is simple and rapid …

Energy-filtered analytical transmission electron microscopy was used to image the
ultrastructure and determine quantitatively the chemical composition of pigment granules of …

Summary 1 Melanin pigments can be classified into two major groups: the brown to black
insoluble eumelanins and the alkali-soluble yellow to reddish-brown pheomelanins. Both …

Several weeks after porcine retinal pigment epithelial (RPE) cell cultures attain confluence,
macroscopically visible brown foci appear. The cuboidal cells that form the foci contain …

This study examined how various genotypes of coat color in mice and guinea pigs are
related to the type and content of melanin and to the levels of free and protein-bound dopa …

Cysteine is known to be involved in pheomelanin synthesis. Available evidence, however,
indicates that glutathione may also play an important role in melanogenesis. This in vitro …

RESULTS Fig. I shows the urinary excretion of 6H5MI-2-C and 5-S-CD. The mean values for
5-S-CD were 36, 34, and 27 µmol/mol creatinine in Groups I, Il, and 111, respectively. No …