Background Taste is an important factor in evaluating the quality of tea. The sweet and
umami tastes are usually well-accepted for consumers, whereas the bitter and astringent …

Heterotrimeric G protein-coupled receptors (GPCRs) comprise the largest receptor family in
mammals and are responsible for the regulation of most physiological functions. Besides …

The sense of taste allows animals to sample chemicals in the environment prior to ingestion.
Of the five basic tastes, sour, the taste of acids, had remained among the most mysterious …

Taste buds are aggregates of 50–100 polarized neuroepithelial cells that detect nutrients
and other compounds. Combined analyses of gene expression and cellular function reveal …

Bitter taste receptors (T2Rs) in the human airway detect harmful compounds, including
secreted bacterial products. Here, using human primary sinonasal air-liquid interface …

Heterotrimeric G proteins are key players in transmembrane signaling by coupling a huge
variety of receptors to channel proteins, enzymes, and other effector molecules. Multiple …

Sweet and umami (the taste of monosodium glutamate) are the main attractive taste
modalities in humans. T1Rs are candidate mammalian taste receptors that combine to …

Mammals can taste a wide repertoire of chemosensory stimuli. Two unrelated families of
receptors (T1Rs and T2Rs) mediate responses to sweet, amino acids, and bitter …

Glucagon-like peptide-1 (GLP-1), released from gut endocrine L cells in response to
glucose, regulates appetite, insulin secretion, and gut motility. How glucose given orally, but …

Summary Glucagon-like peptide-1 (GLP-1) is an enteric hormone that stimulates insulin
secretion and improves glycaemia in type 2 diabetes. Although GLP-1-based treatments are …