Gold nanoparticle-bridge array to improve DNA hybridization efficiency of SERS sensors

X Huang, W Zhao, X Chen, J Li, H Ye, C Li… - Journal of the …, 2022 - ACS Publications
The interfacial mass transfer rate of a target has a significant impact on the sensing
performance. The surface reaction forms a concentration gradient perpendicular to the …

Recent advances in biosensors for in vitro detection and in vivo imaging of DNA methylation

Q Zhang, Y Wu, Q Xu, F Ma, C Zhang - Biosensors and Bioelectronics, 2021 - Elsevier
DNA methylation is the predominant epigenetic modification that participates in many
fundamental cellular processes through posttranscriptional regulation of gene expression …

MicroRNA detection: current technology and research strategies

EA Hunt, D Broyles, T Head… - Annual review of analytical …, 2015 - annualreviews.org
The relatively new field of microRNA (miR) has experienced rapid growth in methodology
associated with its detection and bioanalysis as well as with its role in-omics research …

DNA tetrahedral nanostructure-based electrochemical miRNA biosensor for simultaneous detection of multiple miRNAs in pancreatic carcinoma

D Zeng, Z Wang, Z Meng, P Wang, L San… - … applied materials & …, 2017 - ACS Publications
Specific and sensitive biomarker detection is essential to early cancer diagnosis. In this
study, we demonstrate an ultrasensitive electrochemical biosensor with the ability to detect …

A portable system for isothermal amplification and detection of exosomal microRNAs

J Qian, Q Zhang, M Liu, Y Wang, M Lu - Biosensors and Bioelectronics, 2022 - Elsevier
Abstracts Exosomal microRNAs (miRNAs) play a key role in cell-cell communication to
regulate gene expression in target cells and have great potential as biomarkers for disease …

Anti-inflammatory and antioxidative effects of tetrahedral DNA nanostructures via the modulation of macrophage responses

Q Zhang, S Lin, S Shi, T Zhang, Q Ma… - … applied materials & …, 2018 - ACS Publications
Tetrahedral DNA nanostructures (TDNs) are a new type of nanomaterials that have recently
attracted attention in the field of biomedicine. However, the practical application of …

DNA tetrahedron nanostructures for biological applications: biosensors and drug delivery

N Xie, S Liu, X Yang, X He, J Huang, K Wang - Analyst, 2017 - pubs.rsc.org
With the rapid development of DNA nanotechnology, various DNA nanostructures with
different shapes and sizes have been self-assembled using “bottom-up” fabrication …

Infrared Plasmonic Biosensor with Tetrahedral DNA Nanostructure as Carriers for Label‐Free and Ultrasensitive Detection of miR‐155

X Hui, C Yang, D Li, X He, H Huang, H Zhou… - Advanced …, 2021 - Wiley Online Library
MicroRNAs play an important role in early development, cell proliferation, apoptosis, and
cell death, and are aberrantly expressed in many types of cancers. To understand their …

[HTML][HTML] DNA tetrahedral nanostructures for the biomedical application and spatial orientation of biomolecules

W Wang, M Lin, W Wang, Z Shen, ZS Wu - Bioactive Materials, 2024 - Elsevier
DNA not only plays a vital role in nature as fundamental hereditary material for storing
genetic material, but also serves as well-defined functional material, for example, building …

Electrochemical biosensor for DNA methylation detection through hybridization chain-amplified reaction coupled with a tetrahedral DNA nanostructure

X Chen, J Huang, S Zhang, F Mo, S Su… - … applied materials & …, 2019 - ACS Publications
DNA methylation is a key factor in the pathogenesis of gene expression diseases or
malignancies. Thus, it has become a significant biomarker for the diagnosis and prognosis …