Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery

J Nicolas, S Mura, D Brambilla, N Mackiewicz… - Chemical Society …, 2013 - pubs.rsc.org
Design and functionalization strategies for multifunctional nanocarriers (eg, nanoparticles,
micelles, polymersomes) based on biodegradable/biocompatible polymers intended to be …

Principles of nanoparticle formation by flash nanoprecipitation

WS Saad, RK Prud'homme - Nano Today, 2016 - Elsevier
Rapid precipitation is an efficient approach for engineering materials at the nanoscale. By
controlling solute nucleation and growth rates in solvent precipitation processes, the size of …

Control of polymeric nanoparticle size to improve therapeutic delivery

JW Hickey, JL Santos, JM Williford, HQ Mao - Journal of Controlled …, 2015 - Elsevier
As nanoparticle (NP)-mediated drug delivery research continues to expand, understanding
parameters that govern NP interactions with the biological environment becomes …

[HTML][HTML] Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy

MK Yu, J Park, S Jon - Theranostics, 2012 - ncbi.nlm.nih.gov
Nanomaterials offer new opportunities for cancer diagnosis and treatment. Multifunctional
nanoparticles harboring various functions including targeting, imaging, therapy, and etc …

Thiol-ene “click” reactions and recent applications in polymer and materials synthesis

AB Lowe - Polymer Chemistry, 2010 - pubs.rsc.org
This review highlights examples of recent applications of both the radical-mediated and
base/nucleophile-initiated thiol-ene reactions in polymer and materials synthesis. Initial …

Review of long-wavelength optical and NIR imaging materials: contrast agents, fluorophores, and multifunctional nano carriers

VJ Pansare, S Hejazi, WJ Faenza… - Chemistry of …, 2012 - ACS Publications
The importance of long wavelength and near-infrared (NIR) imaging has dramatically
increased due to the desire to perform whole animal and deep tissue imaging. The adoption …

Functionalisation of nanoparticles for biomedical applications

NTK Thanh, LAW Green - Nano today, 2010 - Elsevier
Nanoparticles with cores composed of inorganic materials such as noble, magnetic metals,
their alloys and oxides, and semiconductors have been most studied and have vast potential …

Liquid antisolvent precipitation and stabilization of nanoparticles of poorly water soluble drugs in aqueous suspensions: Recent developments and future perspective

AA Thorat, SV Dalvi - Chemical Engineering Journal, 2012 - Elsevier
The liquid antisolvent (LAS) precipitation process for production of ultra-fine particles has
been widely researched for a last few decades. In LAS process, precipitation of solute is …

Effect of ligand density, receptor density, and nanoparticle size on cell targeting

DR Elias, A Poloukhtine, V Popik, A Tsourkas - … , biology and medicine, 2013 - Elsevier
It is generally accepted that the presentation of multiple ligands on a nanoparticle (NP)
surface can improve cell targeting; however, little work has been done to determine whether …

Thiol–maleimide “click” chemistry: evaluating the influence of solvent, initiator, and thiol on the reaction mechanism, kinetics, and selectivity

BH Northrop, SH Frayne, U Choudhary - Polymer Chemistry, 2015 - pubs.rsc.org
The mechanism and kinetics of thiol–maleimide “click” reactions carried out under a variety
of conditions have been investigated computationally and using experimental competition …