Coumarin-based near-infrared fluorogenic probes: Recent advances, challenges and future perspectives

Y Fan, Y Wu, J Hou, P Wang, X Peng, G Ge - Coordination Chemistry …, 2023 - Elsevier
Coumarin-based fluorogenic probes have emerged as preferred imaging tools to real-time
and non-invasively monitor target analyte (s) in biological systems, due to their inherent …

[HTML][HTML] Development of Radiotracers for Imaging of the PD-1/PD-L1 Axis

F Krutzek, K Kopka, S Stadlbauer - Pharmaceuticals, 2022 - mdpi.com
Immune checkpoint inhibitor (ICI) therapy has emerged as a major treatment option for a
variety of cancers. Among the immune checkpoints addressed, the programmed death …

Nanocrystals for Deep-Tissue In Vivo Luminescence Imaging in the Near-Infrared Region

Y Yang, Q Jiang, F Zhang - Chemical Reviews, 2023 - ACS Publications
In vivo imaging technologies have emerged as a powerful tool for both fundamental
research and clinical practice. In particular, luminescence imaging in the tissue-transparent …

First Comparison Study of the In Vitro and In Vivo Properties of a Randomly and Site-Specifically Conjugated SPECT/NIRF Monomolecular Multimodal Imaging …

M Privat, PS Bellaye, E Chazeau, C Racoeur… - Bioconjugate …, 2023 - ACS Publications
Among all approaches in molecular imaging, the combination of near-infrared fluorescence
imaging (NIRF) with radioisotopic imaging (PET or SPECT) allows one to benefit from the …

[HTML][HTML] Targeted dual-modal PET/SPECT-NIR imaging: from building blocks and construction strategies to applications

SM Usama, SC Marker, S Hernandez Vargas… - Cancers, 2022 - mdpi.com
Simple Summary Targeted dual-modal imaging agents for whole body PET/SPECT imaging
and fluorescence-guided surgery (FGS) have significant potential to improve surgical …

[HTML][HTML] Recent Developments in PET and SPECT Radiotracers as Radiopharmaceuticals for Hypoxia Tumors

AT Nguyen, HK Kim - Pharmaceutics, 2023 - mdpi.com
Hypoxia, a deficiency in the levels of oxygen, is a common feature of most solid tumors and
induces many characteristics of cancer. Hypoxia is associated with metastases and strong …

Site-specific, platform-based conjugation strategy for the synthesis of dual-labeled immunoconjugates for bimodal PET/NIRF imaging of HER2-positive tumors

P Adumeau, R Raavé, M Boswinkel… - Bioconjugate …, 2022 - ACS Publications
Because positron emission tomography (PET) and optical imaging are very complementary,
the combination of these two imaging modalities is very enticing in the oncology field. Such …

Near-infrared fluorescent Aza-BODIPY dyes: Rational structural design and biomedical imaging

B Zhao, L Liao, Y Zhu, Z Hu, F Wu - Journal of Luminescence, 2023 - Elsevier
Near-infrared dyes have attracted widespread attention due to their intense absorption and
emission in the near-infrared region. As an important class of heteroatom-containing …

[HTML][HTML] Dual-labelling strategies for nuclear and fluorescence molecular imaging: current status and future perspectives

M Kubeil, IIS Martínez, M Bachmann, K Kopka… - Pharmaceuticals, 2022 - mdpi.com
Molecular imaging offers the possibility to investigate biological and biochemical processes
non-invasively and to obtain information on both anatomy and dysfunctions. Based on the …

[HTML][HTML] Fluorescence-Based Mono-and Multimodal Imaging for In Vivo Tracking of Mesenchymal Stem Cells

WS Yun, H Cho, SI Jeon, DK Lim, K Kim - Biomolecules, 2023 - mdpi.com
The advancement of stem cell therapy has offered transformative therapeutic outcomes for a
wide array of diseases over the past decades. Consequently, stem cell tracking has become …