Abstract Background Landau-Kleffner syndrome (LKS) is an acquired aphasia and
electroencephalogram (EEG) abnormalities mainly in temporoparietal areas. SLC26A4 …

Background SLC26A4 gene mutations related to hearing loss patients can obtain good
hearing and speech rehabilitation effects after cochlear implantation (CI). Objective To …

Hearing loss stands as the most prevalent sensory deficit among humans, posing a
significant global health challenge. Projections indicate that by 2050, approximately 10% of …

Recessive variants of SLC26A4 are a common cause of hereditary hearing impairment and
are responsible for non-syndromic enlarged vestibular aqueducts and Pendred syndrome …

For monogenic genetic diseases, in utero gene therapy (IUGT) shows the potential for early
prevention against irreversible and lethal pathological changes. Moreover, animal models …

Abstract Context• Sudden deafness (SSHL) belongs to the category of diseases causing
neurological hearing loss with a sudden and unknown etiology. The pathogenesis and …

BACKGROUND: Menière disease (MD) and SLC26A4 related deafness (Pendred syndrome
(PS) or DFNB4) are two different inner ear disorders which present with fluctuating and …

An increasing number of biological and epidemiological evidence suggests that c. 919-2A>
G and c. 2168A> G variants of solute carrier family 26, member 4 (SLC26A4) gene play a …

Hearing loss is the most frequent sensory disorder affecting newborns and children. About 1
newborn in every 500 suffer from congenital hearing loss, with approximately half of these …

Hearing loss is the most frequent sensory disorder affecting newborns and children. About
1newborn in every 500 suffer from congenital hearing loss, with approximately half of …