Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Endothelial cells are important constituents of blood vessels that play critical roles in
cardiovascular homeostasis by regulating blood fluidity and fibrinolysis, vascular tone …

Hydrogen sulfide (H 2 S) is now recognized as an endogenous signaling gasotransmitter in
mammals. It is produced by mammalian cells and tissues by various enzymes …

Cystathionine-β-synthase (CBS), the first (and rate-limiting) enzyme in the transsulfuration
pathway, is an important mammalian enzyme in health and disease. Its biochemical …

Aims: H2S, a third member of gasotransmitter family along with nitric oxide and carbon
monoxide, exerts a wide range of cellular and molecular actions in our body. Cystathionine …

Background Dysbiosis of the gut microbiome is involved in the pathogenesis of various
diseases, but the contribution of gut microbes to the progression of chronic obstructive …

Chronic obstructive pulmonary disease/emphysema (COPD/emphysema) is characterized
by chronic inflammation and premature lung aging. Anti-aging sirtuin 1 (SIRT1), a NAD+ …

H2S (hydrogen sulfide) is a well known and pungent gas recently discovered to be
synthesized enzymatically in mammalian and human tissues. In a relatively short period of …

At appropriate concentrations, hydrogen sulfide, a well-known gasotransmitter, plays
important roles in both physiology and pathophysiology. Increasing evidence suggests that …

Aims: The signaling molecule hydrogen sulfide (H2S) protects cells against oxidative stress
and activates NF-E2 p45-related factor 2 (Nrf2), a transcription factor that regulates …