The blood-brain barrier (BBB) is a highly specialized brain endothelial structure of the fully
differentiated neurovascular system. In concert with pericytes, astrocytes, and microglia, the …

A general mathematical model for the delivery of O2 to the brain is presented, based on the
assumptions that all of the brain capillaries are perfused at rest and that all of the oxygen …

Imaging techniques based on optical contrast analysis can be used to visualize dynamic
and functional properties of the nervous system via optical signals resulting from changes in …

Using a newly developed perfused rat brain model, we examined direct effects of each
change in cerebral blood flow (CBF) and oxygen metabolic rate on cerebral hemoglobin …

Numerous techniques have been proposed in the last 15 years to measure various
perfusion‐related parameters in the brain. In particular, two approaches have proven …

Vessel size imaging is a new method that is based on simultaneous measurement of the
changes ΔR2 and ΔR in relaxation rate constants induced by the injection of an …

Capillary perfusion in the brain is characterized by an essentially continuous flow of
erythrocytes and plasma in almost all capillaries. Rapid fluctuations and spatial …

The effect of chronic hypobaric hypoxia (28 days, 455 Torr) on the organization of brain
vessels was studied in Balb/c mice. In comparison to age-matched controls kept at sea level …

The hypothesis that functional groups of neurons in whisker barrels are linked to a modular
organization of cortical vessels was tested. Endovascular casts demonstrated cortical …

Preface t the end of the eighteenth century, Franz Joseph Gall postulated that the various
sensory, motor, and cognitive faculties of man arose from different organs and centers of the …