Significance: Current guidelines for rheumatoid arthritis (RA) management recommend early
treatment with disease modifying antirheumatic drugs (DMARDs). However, DMARD …

Graded asymmetric spin echo-echo planar imaging (ASE-EPI) was used to measure
transient alterations in cerebral oxygenation resulting from 60 seconds of anoxia in α …

The purpose of this study was to determine if baseline oxygen pressure (PO2), carbon
dioxide pressure (PCO2), and pH in brain tissue adjacent to an arteriovenous malformation …

Plasma perfusion patterns were investigated in brain capillaries during decreased cerebral
blood flow induced by hyperventilation. Anesthetized rats were decapitated 3-4 s after being …

Both first pass bolus tracking of a susceptibility contrast agent and blood oxygenation level
dependent (BOLD) sequences provide information on the tissue perfusion and the cerebral …

The objective of this study was to generate data that allow for estimation of the validity of
oxygen saturation (S02) values in superficial cortical capillaries as calculated by a …

Objective: To test the capillary recruitment hypothesis for the brain with control and hypoxic
rats. Methods: Local cerebral blood flow (LCBF) was sharply raised by respiring 10% O2 …

The objective of this study was to determine whether hemodilution could normalize the
mean transit times of red blood cells (Tr) and plasma (Tp) through cerebral microvessels in a …

Objective Our aim was to test the feasibility of blood oxygen level dependent magnetic
resonance imaging (BOLD MRI) and dynamic contrast-enhanced (DCE) MRI to monitor …

Brain ischemia (defined here as restricted flow) and/or hypoxia (defined here as a reduced
oxygen supply) caused by stroke is a major cause of death and debilitation. In addition …