Lifestyle and the prevention of type 2 diabetes: a status report

KI Galaviz, KMV Narayan, F Lobelo… - American journal of …, 2018 - journals.sagepub.com
Diabetes is a costly disease affecting 387 million individuals globally and 28 million in the
United States. Its precursor, prediabetes, affects 316 and 86 million individuals globally and …

Gene-environment and gene-treatment interactions in type 2 diabetes: progress, pitfalls, and prospects

PW Franks, E Pearson, JC Florez - Diabetes care, 2013 - Am Diabetes Assoc
Type 2 diabetes has rapidly emerged as a global health crisis. Because population-level
genetic changes take many generations to occur, this epidemic is almost certainly primarily …

[HTML][HTML] Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study

C Langenberg, SJ Sharp, PW Franks, RA Scott… - PLoS …, 2014 - journals.plos.org
In this study, Wareham and colleagues quantified the combined effects of genetic and
lifestyle factors on risk of T2D in order to inform strategies for prevention. The authors found …

Physical activity, sedentary behaviors and the incidence of type 2 diabetes mellitus: the Multi-Ethnic Study of Atherosclerosis (MESA)

JJ Joseph, JB Echouffo-Tcheugui, SH Golden… - BMJ Open Diabetes …, 2016 - drc.bmj.com
Background The association between physical activity (PA), sedentary behavior, and
incident diabetes has been assessed in whites but is less well investigated in multiethnic …

[HTML][HTML] Type 2 diabetes genetics: beyond GWAS

DK Sanghera, PR Blackett - Journal of diabetes & metabolism, 2012 - ncbi.nlm.nih.gov
The global epidemic of type 2 diabetes mellitus (T2D) is one of the most challenging
problems of the 21 st century leading cause of and the fifth death worldwide. Substantial …

[HTML][HTML] Lifestyle and genetics in obesity and type 2 diabetes

T Temelkova-Kurktschiev… - Experimental and clinical …, 2012 - thieme-connect.com
Obesity and type 2 diabetes mellitus are multifactorial health threats caused by a complex
interplay between genetic predisposition and the environment with dramatically increasing …

Gene‐lifestyle interaction on risk of type 2 diabetes: A systematic review

S Dietrich, S Jacobs, JS Zheng, K Meidtner… - Obesity …, 2019 - Wiley Online Library
The pathophysiological influence of gene‐lifestyle interactions on the risk to develop type 2
diabetes (T2D) is currently under intensive research. This systematic review summarizes the …

Genetics of type 2 diabetes

A Stančáková, M Laakso - Novelties in Diabetes, 2016 - karger.com
Genetic and environmental factors as well as their interactions contribute to the
pathogenesis of type 2 diabetes. Linkage analysis, candidate gene approaches, genome …

[HTML][HTML] Islet biology, the CDKN2A/B locus and type 2 diabetes risk

Y Kong, RB Sharma, BU Nwosu, LC Alonso - Diabetologia, 2016 - Springer
Type 2 diabetes, fuelled by the obesity epidemic, is an escalating worldwide cause of
personal hardship and public cost. Diabetes incidence increases with age, and many …

Prevalence of metabolic syndrome among Roma: A comparative health examination survey in Hungary

Z Kósa, Á Moravcsik-Kornyicki… - … European Journal of …, 2015 - academic.oup.com
Objectives: The objective of our study was to compare the health status of the Roma people
with that of the general population in Hungary. Methods: A health examination survey to …