The type II secretion system: biogenesis, molecular architecture and mechanism
KV Korotkov, M Sandkvist, WGJ Hol - Nature Reviews Microbiology, 2012 - nature.com
Many Gram-negative bacteria use the sophisticated type II secretion system (T2SS) to
translocate a wide range of proteins from the periplasm across the outer membrane. The …
translocate a wide range of proteins from the periplasm across the outer membrane. The …
The structure and mechanism of the bacterial type II secretion system
The type II secretion system (T2SS) is a multi‐protein complex used by many bacteria to
move substrates across their cell membrane. Substrates released into the environment …
move substrates across their cell membrane. Substrates released into the environment …
Type II secretion: from structure to function
TL Johnson, J Abendroth, WGJ Hol… - FEMS microbiology …, 2006 - academic.oup.com
abstract Gram-negative bacteria use the type II secretion system to transport a large number
of secreted proteins from the periplasmic space into the extracellular environment. Many of …
of secreted proteins from the periplasmic space into the extracellular environment. Many of …
Systematic Identification of Cyclic-di-GMP Binding Proteins in Vibrio cholerae Reveals a Novel Class of Cyclic-di-GMP-Binding ATPases Associated with Type II …
Cyclic-di-GMP (c-di-GMP) is a ubiquitous bacterial signaling molecule that regulates a
variety of complex processes through a diverse set of c-di-GMP receptor proteins. We have …
variety of complex processes through a diverse set of c-di-GMP receptor proteins. We have …
Architecture, function, and substrates of the type II secretion system
KV Korotkov, M Sandkvist - EcoSal Plus, 2019 - Am Soc Microbiol
The type II secretion system (T2SS) delivers toxins and a range of hydrolytic enzymes,
including proteases, lipases, and carbohydrate-active enzymes, to the cell surface or …
including proteases, lipases, and carbohydrate-active enzymes, to the cell surface or …
PilB and PilT Are ATPases Acting Antagonistically in Type IV Pilus Function in Myxococcus xanthus
V Jakovljevic, S Leonardy, M Hoppert… - Journal of …, 2008 - Am Soc Microbiol
ABSTRACT Type IV pili (T4P) are dynamic surface structures that undergo cycles of
extension and retraction. T4P dynamics center on the PilB and PilT proteins, which are …
extension and retraction. T4P dynamics center on the PilB and PilT proteins, which are …
Virulence factors, pathogenesis and vaccine protection in cholera and ETEC diarrhea
J Sánchez, J Holmgren - Current opinion in immunology, 2005 - Elsevier
Recent work has provided new insights into the pathogenesis of the potentially life-
threatening diarrheas caused by Vibrio cholerae and enterotoxigenic Escherichia coli …
threatening diarrheas caused by Vibrio cholerae and enterotoxigenic Escherichia coli …
Protein traffic in Gram-negative bacteria–how exported and secreted proteins find their way
RE Dalbey, A Kuhn - FEMS microbiology reviews, 2012 - academic.oup.com
Gram-negative bacteria assemble many proteins into the inner and outer membranes and
export a large number of proteins to the periplasm or to the extracellular medium. During the …
export a large number of proteins to the periplasm or to the extracellular medium. During the …
On the path to uncover the bacterial type II secretion system
Gram-negative bacteria have evolved several secretory pathways to release enzymes or
toxins into the surrounding environment or into the target cells. The type II secretion system …
toxins into the surrounding environment or into the target cells. The type II secretion system …
AB toxins: a paradigm switch from deadly to desirable
To ensure their survival, a number of bacterial and plant species have evolved a common
strategy to capture energy from other biological systems. Being imperfect pathogens …
strategy to capture energy from other biological systems. Being imperfect pathogens …