A review and database of snake venom proteomes

T Tasoulis, GK Isbister - Toxins, 2017 - mdpi.com
Advances in the last decade combining transcriptomics with established proteomics
methods have made possible rapid identification and quantification of protein families in …

Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms

B Lomonte, JJ Calvete - Journal of Venomous Animals and Toxins …, 2017 - SciELO Brasil
This work offers a general overview on the evolving strategies for the proteomic analysis of
snake venoms, and discusses how these may be combined through diverse experimental …

A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite

LO Albulescu, C Xie, S Ainsworth, J Alsolaiss… - Nature …, 2020 - nature.com
Snakebite is a medical emergency causing high mortality and morbidity in rural tropical
communities that typically experience delayed access to unaffordable therapeutics. Viperid …

Old World Vipers—a review about snake venom proteomics of Viperinae and their variations

M Damm, BF Hempel, RD Süssmuth - Toxins, 2021 - mdpi.com
Fine-tuned by millions of years of evolution, snake venoms have frightened but also
fascinated humanity and nowadays they constitute potential resources for drug …

Phylovenomics of Daboia russelii across the Indian subcontinent. Bioactivities and comparative in vivo neutralization and in vitro third-generation antivenomics of …

D Pla, L Sanz, S Quesada-Bernat, M Villalta, J Baal… - Journal of …, 2019 - Elsevier
Russell's viper (Daboia russelii) is, together with Naja naja, Bungarus caeruleus and Echis
carinatus, a member of the medically important 'Big Four'species responsible for causing a …

Venom proteomics and antivenom neutralization for the Chinese eastern Russell's viper, Daboia siamensis from Guangxi and Taiwan

KY Tan, NH Tan, CH Tan - Scientific reports, 2018 - nature.com
The eastern Russell's viper (Daboia siamensis) causes primarily hemotoxic envenomation.
Applying shotgun proteomic approach, the present study unveiled the protein complexity …

Minor snake venom proteins: Structure, function and potential applications

J Boldrini-Franca, CT Cologna, MB Pucca… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Snake venoms present a great diversity of pharmacologically active compounds that may be
applied as research and biotechnological tools, as well as in drug development and …

Proteomic analysis reveals geographic variation in venom composition of Russell's Viper in the Indian subcontinent: Implications for clinical manifestations post …

B Kalita, SP Mackessy… - Expert review of proteomics, 2018 - Taylor & Francis
ABSTRACT Introduction: The Russell's Viper (RV)(Daboia russelii), a category I medically
important snake, is responsible for a significant level of morbidity and mortality in the Indian …

Proteomics, functional characterization and antivenom neutralization of the venom of Pakistani Russell's viper (Daboia russelii) from the wild

T Faisal, KY Tan, SM Sim, N Quraishi, NH Tan… - Journal of …, 2018 - Elsevier
The venom proteome of wild Pakistani Russell's viper (Daboia russelii) was investigated
through nano-ESI-LCMS/MS of the reverse-phase HPLC fractions. A total of 54 venom …

Unraveling the proteome composition and immuno-profiling of western India Russell's viper venom for in-depth understanding of its pharmacological properties …

B Kalita, A Patra, AK Mukherjee - Journal of proteome research, 2017 - ACS Publications
The proteome composition of western India (WI) Russell's viper venom (RVV) was correlated
with pharmacological properties and pathological manifestations of RV envenomation …