Psoriasis between autoimmunity and oxidative stress: changes induced by different therapeutic approaches

MV Medovic, VL Jakovljevic, VI Zivkovic… - Oxidative medicine …, 2022 - Wiley Online Library
Psoriasis is defined as chronic, immune‐mediated disease. Regardless of the development
of new therapeutic approaches, the precise etiology of psoriasis remains unknown and …

Th17 cells and IL-17A in ischemic stroke

J Wang, Y Gao, Y Yuan, H Wang, Z Wang… - Molecular …, 2024 - Springer
The neurological injury and repair mechanisms after ischemic stroke are complex. The
inflammatory response is present throughout stroke onset and functional recovery, in which …

Potential cerebrovascular accident signal for risankizumab: a disproportionality analysis of the FDA adverse event reporting system (FAERS)

RH Woods - British Journal of Clinical Pharmacology, 2023 - Wiley Online Library
Aims The interleukin‐23 (IL‐23) inhibitor risankizumab was recently approved for the
treatment of moderate‐to‐severe plaque psoriasis in the United States. Low rates of …

Interleukins in epilepsy: friend or foe

Y Dong, X Zhang, Y Wang - Neuroscience Bulletin, 2024 - Springer
Epilepsy is a chronic neurological disorder with recurrent unprovoked seizures, affecting~
65 million worldwide. Evidence in patients with epilepsy and animal models suggests a …

An integrated analysis of hypoxic–ischemic encephalopathy‐related cell sequencing outcomes via genes network construction

HS Zhou, TB Chen - Ibrain, 2022 - Wiley Online Library
Hypoxic–ischemic encephalopathy (HIE) is one of the main causes of morbidity and severe
neurological deficits in neonates. This study aimed to find core genes and their potential …

Effects of Different Therapeutic Approaches on Redox Balance in Psoriatic Patients

MV Medovic, VM Milicic, ABR Nikolic, GJ Ristic… - Biomedicines, 2024 - mdpi.com
Given that oxidative stress represents an important etiological factor in the pathogenesis of
psoriasis, the aim of this study was to assess the effects of different therapeutic approaches …

基于miR-155/JAK2/STAT3 信号通路探讨仙茅苷减轻大鼠心肌缺血再灌注损伤作用机制

李红英, 刘佳, 张会军, 董彦博… - 华中科技大学学报(医学 …, 2024 - tjqk.magtech.com.cn
摘要: 目的探讨仙茅苷对心肌缺血再灌注(I/R) 大鼠心肌损伤的改善作用及对微小RNA (miR)-
155/Janus 蛋白酪氨酸激酶2/信号转导及转录激活蛋白3 (JAK2/STAT3) 信号通路的调节作用 …

贯叶金丝桃对大鼠脑缺血再灌注损伤的保护作用及机制研究

王宏, 康利, 江茜, 刘伟伟, 张岩, 傅予 - 中国药房, 2023 - journal.china-pharmacy.com
目的探讨贯叶金丝桃对大鼠脑缺血再灌注损伤的保护作用及潜在机制. 方法将雄性SD
大鼠随机分为假手术组, 模型组, 阳性对照组(尼莫地平0.012 g/kg) 和贯叶金丝桃高 …

Effect of lipoxin A4 methyl ester from arachidonic acid on JAK2/STAT3 pathway after cerebral ischemia-reperfusion injury

X Ye, Y Wu, Q CHEN, H Song, J Cheng - Food Science and …, 2023 - SciELO Brasil
It was determined if lipoxin A4 methyl ester (LXA4 ME) affects JAK2/STAT3 pathway
following transient focal cerebral ischemia-reperfusion injury (CIRI) in rats. Adult male SD …

[PDF][PDF] Study on Mechanism of Curculigoside Alleviating Myocardial Ischemia-Reperfusion Injury in Rats Based on miR-155/JAK2/STAT3 Signaling Pathway

L Hongying, L Jia, Z Huijun - Acta Medicinae Universitatis …, 2024 - tjqk.magtech.com.cn
目的 探讨仙茅苷对心肌缺血再灌注 (I/R) 大鼠心肌损伤的改善作用及对微小 RNA (miR)-
155/Janus 蛋白酪氨酸激酶 2/信号转导及转录激活蛋白 3 (JAK2/STAT3) 信号通路的调节作用 …