Colorectal cancer (CRC), the third most common type of cancer, is the second leading cause
of cancer-related mortality rates worldwide. Although modern research was able to shed …

Abstract Background Approximately 5.0–24.2% of colorectal cancers (CRCs) have
inactivating mutations in SMAD4, making it one of the frequently mutated genes in CRC. We …

The human epidermal growth factor receptor (HER, ErbB) family has four members,
epidermal growth factor receptor (EGFR), HER2, HER3, and HER4. Although distinct in …

According to data from 2020, Slovakia has long been among the top five countries with the
highest incidence rate of colorectal cancer (CRC) worldwide, and the rate is continuing to …

This study explored the roles of activins and follistatin in colorectal cancers. Paired
malignant and normal colonic tissues were collected from archived paraffin-embedded (n …

Background Ovarian cancer ranks fifth among the most prevalent cancer type in females all
over the world. It is the second most frequent malignant tumor which accounts for 3% of …

Background Colorectal cancer (CRC) is a heterogeneous cancer. Its treatment depends on
its anatomical site and molecular features. Carcinomas of the rectosigmoid junction are …

Systemic characterization of genomic alterations into signaling pathways helps to
understand the molecular pathogenies of colorectal cancer; however, their clinical …

Feline oral squamous cell carcinoma (FOSCC) is characterised by invasive and metastatic
behaviour and is poorly responsive to current treatments, hence the need for new …

Background Epithelial–mesenchymal transition (EMT) is a key step in the development of
colorectal cancer (CRC) that confers metastatic capabilities to cancer cells. The present …