A promising therapeutic window and cost-effectiveness are just two of the potential
advantages of using naturally derived drugs. Fisetin (3, 3′, 4′, 7-tetrahydroxyflavone) is a …

Fisetin (FIS), a senolytic flavonoid, mitigates age-related neuroprotective changes. An
amorphous FIS dispersion with a co-carrier was prepared using supercritical fluid extraction …

Fisetin has displayed potential as an anticonvulsant in preclinical studies yet lacks clinical
validation. Challenges like low solubility and rapid metabolism may limit its efficacy. This …

Alzheimer's disease (AD) is a neurodegenerative disorder marked by cognitive impairment
and memory loss. In this study, AD was experimentally induced in rats using aluminum …

The anticancer potential and associated mechanisms of flavonoid fisetin are yet to be fully
investigated on human head and neck squamous cell carcinoma (HNSCC). In the present …

In this study, binary amorphous solid dispersions (ASDs, fisetin-Eudragit®) and ternary
amorphous solid inclusions (ASIs, fisetin-Eudragit®-HP-β-cyclodextrin) of fisetin (FIS) were …

Despite their subordination in humans, to a great extent, mitochondria maintain their
independent status but tightly cooperate with the “host” on protecting the joint life quality and …

Aim: To prepare fisetin (FIS) cubosomal nanoformulation to increase aqueous solubility and
anticancer activity. Methods: Top-down method using glyceryl monooleate (GMO) and …

Flavonoids, including fisetin, have been linked to a reduced risk of colorectal cancer (CRC)
and have potential therapeutic applications for the condition. Fisetin, a natural flavonoid …