[HTML][HTML] The current status of latency reversing agents for HIV-1 remission
A Rodari, G Darcis, CM Van Lint - Annual review of virology, 2021 - annualreviews.org
Combinatory antiretroviral therapy (cART) reduces human immunodeficiency virus type 1
(HIV-1) replication but is not curative because cART interruption almost invariably leads to a …
(HIV-1) replication but is not curative because cART interruption almost invariably leads to a …
[HTML][HTML] The reservoir of latent HIV
J Chen, T Zhou, Y Zhang, S Luo, H Chen… - Frontiers in cellular …, 2022 - frontiersin.org
The persistence of latent reservoir of the human immunodeficiency virus (HIV) is currently
the major challenge in curing HIV infection. After HIV infects the human body, the latent HIV …
the major challenge in curing HIV infection. After HIV infects the human body, the latent HIV …
[HTML][HTML] Pyrroles as privileged scaffolds in the search for new potential HIV inhibitors
Acquired immunodeficiency syndrome (AIDS) is caused by human immunodeficiency virus
(HIV) and remains a global health problem four decades after the report of its first case …
(HIV) and remains a global health problem four decades after the report of its first case …
[HTML][HTML] Defective HIV-1 genomes and their potential impact on HIV pathogenesis
J Kuniholm, C Coote, AJ Henderson - Retrovirology, 2022 - Springer
Defective HIV-1 proviruses represent a population of viral genomes that are selected for by
immune pressures, and clonally expanded to dominate the persistent HIV-1 proviral genome …
immune pressures, and clonally expanded to dominate the persistent HIV-1 proviral genome …
[HTML][HTML] A Review of the development of multitarget molecules against HIV-TB coinfection pathogens
DI Leite, S de Castro Bazan Moura… - Molecules, 2023 - mdpi.com
The human immunodeficiency virus (HIV) produces the pathologic basis of acquired
immunodeficiency syndrome (AIDS). An increase in the viral load in the body leads to a …
immunodeficiency syndrome (AIDS). An increase in the viral load in the body leads to a …
[HTML][HTML] Humanized mice for studies of HIV-1 persistence and elimination
A major roadblock to achieving a cure for human immunodeficiency virus type one (HIV-1) is
the persistence of latent viral infections in the cells and tissue compartments of an infected …
the persistence of latent viral infections in the cells and tissue compartments of an infected …
[HTML][HTML] Fighting HIV-1 persistence: At the crossroads of “shoc-K and B-Lock”
Despite the success of highly active antiretroviral therapy (HAART), integrated HIV-1 proviral
DNA cannot be eradicated from an infected individual. HAART is not able to eliminate …
DNA cannot be eradicated from an infected individual. HAART is not able to eliminate …
[HTML][HTML] The splice of life: does RNA processing have a role in HIV-1 persistence?
AO Pasternak, B Berkhout - Viruses, 2021 - mdpi.com
Antiretroviral therapy (ART) suppresses HIV-1 replication but does not eradicate the virus.
Persistence of HIV-1 latent reservoirs in ART-treated individuals is considered the main …
Persistence of HIV-1 latent reservoirs in ART-treated individuals is considered the main …
Analysis of the contribution of 6-mer seed toxicity to HIV-1-induced cytopathicity
ABSTRACT HIV-1 (HIV) infects CD4+ T cells, the gradual depletion of which can lead to
AIDS in the absence of antiretroviral therapy (ART). Some cells, however, survive HIV …
AIDS in the absence of antiretroviral therapy (ART). Some cells, however, survive HIV …
[HTML][HTML] Antibody conjugates for targeted therapy against HIV-1 as an emerging tool for HIV-1 cure
JC Umotoy, SW De Taeye - Frontiers in immunology, 2021 - frontiersin.org
Although advances in antiretroviral therapy (ART) have significantly improved the life
expectancy of people living with HIV-1 (PLWH) by suppressing HIV-1 replication, a cure for …
expectancy of people living with HIV-1 (PLWH) by suppressing HIV-1 replication, a cure for …