[HTML][HTML] Impact of lipid nanoparticle size on mRNA vaccine immunogenicity
KJ Hassett, J Higgins, A Woods, B Levy, Y Xia… - Journal of Controlled …, 2021 - Elsevier
Lipid nanoparticles (LNP) are effective delivery vehicles for messenger RNA (mRNA) and
have shown promise for vaccine applications. Yet there are no published reports detailing …
have shown promise for vaccine applications. Yet there are no published reports detailing …
Particle detection and characterization for biopharmaceutical applications: current principles of established and alternative techniques
J Gross-Rother, M Blech, E Preis, U Bakowsky… - Pharmaceutics, 2020 - mdpi.com
Detection and characterization of particles in the visible and subvisible size range is critical
in many fields of industrial research. Commercial particle analysis systems have proliferated …
in many fields of industrial research. Commercial particle analysis systems have proliferated …
[HTML][HTML] Harnessing dendritic cells for poly (D, L-lactide-co-glycolide) microspheres (PLGA MS)—Mediated anti-tumor therapy
J Koerner, D Horvath, M Groettrup - Frontiers in immunology, 2019 - frontiersin.org
With emerging success in fighting off cancer, chronic infections, and autoimmune diseases,
immunotherapy has become a promising therapeutic approach compared to conventional …
immunotherapy has become a promising therapeutic approach compared to conventional …
Size, stability, and porosity of mesoporous nanoparticles characterized with light scattering
M Kaasalainen, V Aseyev, E von Haartman… - Nanoscale research …, 2017 - Springer
Silicon-based mesoporous nanoparticles have been extensively studied to meet the
challenges in the drug delivery. Functionality of these nanoparticles depends on their …
challenges in the drug delivery. Functionality of these nanoparticles depends on their …
Considerations for size, surface charge, polymer degradation, co‐delivery, and manufacturability in the development of polymeric particle vaccines for infectious …
Vaccines have advanced human health for centuries. To improve upon the efficacy of
subunit vaccines they have been formulated into nano/microparticles for infectious diseases …
subunit vaccines they have been formulated into nano/microparticles for infectious diseases …
Mouse models for assessing protein immunogenicity: lessons and challenges
W Jiskoot, G Kijanka, TW Randolph… - Journal of …, 2016 - Elsevier
The success of clinical and commercial therapeutic proteins is rapidly increasing, but their
potential immunogenicity is an ongoing concern. Most of the studies that have been …
potential immunogenicity is an ongoing concern. Most of the studies that have been …
Protein supramolecular structures: from self-assembly to nanovaccine design
Life-inspired protein supramolecular assemblies have recently attracted considerable
attention for the development of next-generation vaccines to fight against infectious …
attention for the development of next-generation vaccines to fight against infectious …
Biodegradable microrobots for DNA vaccine delivery
The delivery of nucleic acid vaccine to stimulate host immune responses against
Coronavirus disease 2019 shows promise. However, nucleic acid vaccines have …
Coronavirus disease 2019 shows promise. However, nucleic acid vaccines have …
[HTML][HTML] Virus-like particle, liposome, and polymeric particle-based vaccines against HIV-1
Y Gao, C Wijewardhana, JFS Mann - Frontiers in Immunology, 2018 - frontiersin.org
It is acknowledged that vaccines remain the best hope for eliminating the HIV-1 epidemic.
However, the failure to produce effective vaccine immunogens and the inability of …
However, the failure to produce effective vaccine immunogens and the inability of …
DNA vaccination for finfish aquaculture
C Collins, N Lorenzen, B Collet - Fish & shellfish immunology, 2019 - Elsevier
In fish, DNA vaccines have been shown to give very high protection in experimental facilities
against a number of viral diseases, particularly diseases caused by rhabdoviruses …
against a number of viral diseases, particularly diseases caused by rhabdoviruses …