Immune responses participate in every phase of atherosclerosis. There is increasing
evidence that both adaptive and innate immunity tightly regulate atherogenesis. Although …

Beyond an eminent role in hemostasis and thrombosis, platelets are characterized by expert
functions in assisting and modulating inflammatory reactions and immune responses. This is …

Platelets are the main players in thrombosis and hemostasis; however they also play
important roles during inflammation and infection. Through their surface receptors, platelets …

Although mounting evidence indicates that platelets participate in the modulation of both
innate and adaptive immunity, the mechanisms by which platelets exert these effects have …

CD40, a transmembrane receptor of the tumor necrosis factor gene superfamily is expressed
on a variety of cells, such as monocytes, B‐cells, antigen presenting cells, endothelial …

Small fragments circulating in the blood were formally identified by the end of the nineteenth
century, and it was suggested that they assisted coagulation via interactions with vessel …

Platelets and lymphocytes reciprocally regulate mutual functions, ie, platelet–lymphocyte
cross-talk. The heterotypic interactions have emerged as important regulatory mechanisms …

The manifestation of platelet 'satallitism'around neutrophils in whole blood is a long
acknowledged phenomenon [1]. Circulating platelet–neutrophil complexes (PNC) occur in a …

Macrophages reside in all tissues as resident populations and as immigrants recruited in
response to tissue injury, inflammation or pathogen invasion. Under normal conditions …

The immune system is comprised of two principal interconnected components called innate
and adaptive immunity. While the innate immune system mounts a nonspecific response that …