Brain, the major organ of the central nervous system controls and processes most of body
activities. Therefore, the most aggressive brain tumor–glioblastoma and metastases from …

Cancer stem cells (CSCs) are self-renewing cells that facilitate tumor initiation, promote
metastasis, and enhance cancer therapy resistance. Transcriptomic analyses across many …

Cancer stem cells (CSCs) are a subpopulation of cancer cells with functions similar to those
of normal stem cells. Although few in number, they are capable of self-renewal, unlimited …

Radiotherapy (RT) is a modality of oncologic treatment that can be used to treat
approximately 50% of all cancer patients either alone or in combination with other treatment …

Cancer stem cells (CSCs) represent a tumor subpopulation responsible for tumor metastasis
and resistance to chemo-and radiotherapy, ultimately leading to tumor relapse. As a …

Therapy resistance is a major problem when treating cancer patients as cancer cells
develop mechanisms that counteract the effect of therapeutic compounds, leading to fit and …

Lipids, the basic components of the cell membrane, execute fundamental roles in almost all
the cell activities including cell-cell recognition, signalling transduction and energy supplies …

The prominent role of CD44 in tumor cell signaling together with its establishment as a
cancer stem cell (CSC) marker for various tumor entities imply a key role for CD44 in CSC …

Background Myeloid-derived suppressor cells (MDSCs) and cancer stem cells (CSCs) are
two important cellular components in the tumor microenvironment, which may modify the …

The function of vascular endothelial growth factor (VEGF) in cancer extends beyond
angiogenesis and vascular permeability. Specifically, VEGF-mediated signaling occurs in …