Chronic pain and neuroinflammation
P Vergne-Salle, P Bertin - Joint Bone Spine, 2021 - Elsevier
In rheumatology, chronic pain most often sets in after a musculoskeletal injury. Its
persistence is not always due to the progression of the initial injury, but in some cases to the …
persistence is not always due to the progression of the initial injury, but in some cases to the …
A novel progress: glial cells and inflammatory pain
H Wang, C Xu - ACS Chemical Neuroscience, 2022 - ACS Publications
Inflammatory pain is the perception of noxious stimuli that occurs during inflammation or an
immune response. Glial cells are widespread in the central and peripheral nervous systems …
immune response. Glial cells are widespread in the central and peripheral nervous systems …
Neuroimmune signatures in chronic low back pain subtypes
Z Alshelh, L Brusaferri, A Saha, E Morrissey, P Knight… - Brain, 2022 - academic.oup.com
We recently showed that patients with different chronic pain conditions (such as chronic low
back pain, fibromyalgia, migraine and Gulf War illness) demonstrated elevated brain and/or …
back pain, fibromyalgia, migraine and Gulf War illness) demonstrated elevated brain and/or …
Bidirectional action of cenicriviroc, a CCR2/CCR5 antagonist, results in alleviation of pain-related behaviors and potentiation of opioid analgesia in rats with peripheral …
K Kwiatkowski, K Pawlik, K Ciapała… - Frontiers in …, 2020 - frontiersin.org
Clinical management of neuropathic pain is unsatisfactory, mainly due to its resistance to the
effects of available analgesics, including opioids. Converging evidence indicates the …
effects of available analgesics, including opioids. Converging evidence indicates the …
Neuromechanobiology: an expanding field driven by the force of greater focus
The brain processes information by transmitting signals through highly connected and
dynamic networks of neurons. Neurons use specific cellular structures, including axons …
dynamic networks of neurons. Neurons use specific cellular structures, including axons …
[HTML][HTML] Nutraceuticals: A source of benefaction for neuropathic pain and fibromyalgia
Though both neuropathy and fibromyalgia are serious complications that cause widespread
pain, distinguishing between the two in order to provide adequate care is difficult. Metabolic …
pain, distinguishing between the two in order to provide adequate care is difficult. Metabolic …
[HTML][HTML] Role of microglia in neuropathic pain
MY Karavis, I Siafaka, A Vadalouca, G Georgoudis - Cureus, 2023 - ncbi.nlm.nih.gov
Microglial cells are specialized macrophage cells of the central nervous system responsible
for the innate immunity of the spinal cord and the brain. They protect the brain and spinal …
for the innate immunity of the spinal cord and the brain. They protect the brain and spinal …
[HTML][HTML] Resident immune responses to spinal cord injury: role of astrocytes and microglia
Spinal cord injury can be traumatic or non-traumatic in origin, with the latter rising in
incidence and prevalence with the aging demographics of our society. Moreover, as the …
incidence and prevalence with the aging demographics of our society. Moreover, as the …
Biodegradable nanoparticles targeting circulating immune cells reduce central and peripheral sensitization to alleviate neuropathic pain following spinal cord injury
MN Saunders, KV Griffin, I Kalashnikova, D Kolpek… - Pain, 2024 - journals.lww.com
Neuropathic pain is a critical source of comorbidity following spinal cord injury (SCI) that can
be exacerbated by immune-mediated pathologies in the central and peripheral nervous …
be exacerbated by immune-mediated pathologies in the central and peripheral nervous …
Component-target network and mechanism of Qufeng Zhitong capsule in the treatment of neuropathic pain
Y Liao, J Wang, J Zhang, C Guo, X Xu, K Wang… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Qufeng Zhitong capsule (QFZTC) is a traditional
Chinese medicine (TCM) clinically used for treating pain. However, the active ingredients of …
Chinese medicine (TCM) clinically used for treating pain. However, the active ingredients of …