Corticostriatal circuits through the orbitofrontal cortex (OFC) play key roles in complex
human behaviors such as evaluation, affect regulation and reward-based decision-making …

Brain-imaging studies suggest that antisocial and violent behavior is associated with
structural and functional deficits in the prefrontal cortex, but there is heterogeneity in findings …

Alcoholism results from an interplay between genetic and environmental factors, and is
linked to brain defects and associated cognitive, emotional, and behavioral impairments. A …

A common feature of the antisocial, rule-breaking behavior that is central to criminal, violent
and psychopathic individuals is the failure to follow moral guidelines. This review …

Converging evidence from human lesion, animal lesion, and human functional
neuroimaging studies implicates overlapping neural circuitry in ventral prefrontal cortex in …

Psychopaths impose large costs on society, as they are frequently habitual, violent criminals.
The pervasive nature of emotional and behavioral symptoms in psychopathy suggests that …

Introduction Core psychopathy is characterized by grandiosity, callousness,
manipulativeness, and lack of remorse, empathy, and guilt. It is often comorbid with conduct …

Context The population of men who display persistent antisocial and violent behavior is
heterogeneous. Callous-unemotional traits in childhood and psychopathic traits in …

BACKGROUND: Although studies of neurologic patients have suggested that prefrontal
structural impairments may predispose to sociopathy, it is unknown whether there is a …

Brain imaging studies of adults with psychopathy have identified structural and functional
abnormalities in limbic and prefrontal regions that are involved in emotion recognition …