Artemisinin-based combination therapies (ACTs): best hope for malaria treatment but inaccessible to the needy!

TK Mutabingwa - Acta tropica, 2005 - Elsevier
Artemisinin-based combination therapies (ACTs) are the best anti-malarial drugs available
now. Artemisinin enhances efficacy and has the potential of lowering the rate at which …

How patients take malaria treatment: a systematic review of the literature on adherence to antimalarial drugs

K Bruxvoort, C Goodman, SP Kachur, D Schellenberg - PloS one, 2014 - journals.plos.org
Background High levels of patient adherence to antimalarial treatment are important in
ensuring drug effectiveness. To achieve this goal, it is important to understand levels of …

A randomized, double-blind, phase 2b study to investigate the efficacy, safety, tolerability and pharmacokinetics of a single-dose regimen of ferroquine with …

Y Adoke, R Zoleko-Manego, S Ouoba, AB Tiono… - Malaria Journal, 2021 - Springer
Abstract Background For uncomplicated Plasmodium falciparum malaria, highly efficacious
single-dose treatments are expected to increase compliance and improve treatment …

Adherence to artemisinin-based combination therapy for the treatment of malaria: a systematic review of the evidence

K Banek, M Lalani, SG Staedke, D Chandramohan - Malaria journal, 2014 - Springer
Background Increasing access to and targeting of artemisinin-based combination therapy
(ACT) is a key component of malaria control programmes. To maximize efficacy of ACT and …

Artemisia annua as a self-reliant treatment for malaria in developing countries

S De Ridder, F van der Kooy, R Verpoorte - Journal of ethnopharmacology, 2008 - Elsevier
Malaria is a vector-borne infectious disease caused by the protozoan Plasmodium parasites.
Each year, it causes disease in approximately 515 million people and kills between one and …

How do patients use antimalarial drugs? A review of the evidence

S Yeung, NJ White - Tropical Medicine & International Health, 2005 - Wiley Online Library
Patient adherence is a major determinant of the therapeutic response to antimalarial drugs,
as most treatments are taken at home without medical supervision. With the introduction of …

Adherence to a six-dose regimen of artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Uganda.

C Fogg, F Bajunirwe, P Piola, S Biraro, F Checchi… - 2004 - nru.uncst.go.ug
Measuring baseline levels of adherence and identifying risk factors for non-adherence are
important steps before the introduction of new antimalarials. In Mbarara in southwestern …

Emergency obstetric care as the priority intervention to reduce maternal mortality in Uganda

AK Mbonye, JB Asimwe, J Kabarangira… - International Journal of …, 2007 - Elsevier
PURPOSE: We conducted a survey to determine availability of emergency obstetric care
(EmOC) to provide baseline data for monitoring provision of obstetric care services in …

Effectiveness of quinine versus artemether-lumefantrine for treating uncomplicated falciparum malaria in Ugandan children: randomised trial

J Achan, JK Tibenderana, D Kyabayinze, FW Mangen… - Bmj, 2009 - bmj.com
Objective To compare the effectiveness of oral quinine with that of artemether-lumefantrine
in treating uncomplicated malaria in children. Design Randomised, open label effectiveness …

Use of over-the-counter malaria medicines in children and adults in three districts in Kenya: implications for private medicine retailer interventions

TO Abuya, W Mutemi, B Karisa, SA Ochola, G Fegan… - Malaria journal, 2007 - Springer
Background Global malaria control strategies highlight the need to increase early uptake of
effective antimalarials for childhood fevers in endemic settings, based on a presumptive …