Theranostic applications of selenium nanomedicines against lung cancer

S Liu, W Wei, J Wang, T Chen - Journal of Nanobiotechnology, 2023 - Springer
The incidence and mortality rates of lung cancer are among the highest in the world.
Traditional treatment methods include surgery, chemotherapy, and radiotherapy. Although …

Selenium: From fluorescent probes to biomedical application

J Wang, M Chen, Z Zhang, L Ma, T Chen - Coordination Chemistry Reviews, 2023 - Elsevier
Selenium (Se) is of fundamental importance to human health as an essential trace element,
mainly through regulation of selenoproteins (SePs). Therefore, monitoring Se transformation …

Oral hydrogel microbeads-mediated in situ synthesis of selenoproteins for regulating intestinal immunity and microbiota

J Ouyang, B Deng, B Zou, Y Li, Q Bu… - Journal of the …, 2023 - ACS Publications
Selenoprotein plays a crucial role in immune cells and inflammatory regulation. However, as
a protein drug that is easily denatured or degraded in the acidic environment of the stomach …

Emergency treatment and photoacoustic assessment of spinal cord injury using reversible dual‐signal transform‐based selenium antioxidant

Z Ji, J Zheng, Y Ma, H Lei, W Lin, J Huang, H Yang… - Small, 2023 - Wiley Online Library
Spinal cord injury (SCI), following explosive oxidative stress, causes an abrupt and
irreversible pathological deterioration of the central nervous system. Thus, preventing …

Selenoprotein‐Regulated Hydrogel for Ultrasound‐Controlled Microenvironment Remodeling to Promote Bone Defect Repair

R Xu, Y You, W Zheng, L Ma, Y Chang… - Advanced Functional …, 2024 - Wiley Online Library
Abnormal levels of reactive oxygen species (ROS) and the hypoxic microenvironment within
bone defects are important factors that impede bone repair processes. Herein, an innovative …

Novel insights into the synergistic effects of selenium nanoparticles and metformin treatment of letrozole-induced polycystic ovarian syndrome: targeting PI3K/Akt …

HM Rabah, DA Mohamed, RA Mariah… - Redox …, 2023 - Taylor & Francis
Purpose Polycystic ovary syndrome (PCOS) has a series of reproductive and metabolic
consequences. Although the link between PCOS, IR, and obesity, their impact on the …

Nanoparticle formulations of antioxidants for the management of oxidative stress in stroke: A review

S Salatin, M Farhoudi, A Farjami, S Maleki Dizaj… - Biomedicines, 2023 - mdpi.com
Stroke is currently one of the primary causes of morbidity and mortality worldwide.
Unfortunately, there has been a lack of effective stroke treatment. Therefore, novel treatment …

CD44-targeting hyaluronic acid-selenium nanoparticles boost functional recovery following spinal cord injury

W Luo, Y Li, J Zhao, R Niu, C Xiang, M Zhang… - Journal of …, 2024 - Springer
Background Therapeutic strategies based on scavenging reactive oxygen species (ROS)
and suppressing inflammatory cascades are effective in improving functional recovery after …

Advanced application of nanotechnology in active constituents of Traditional Chinese Medicines

C Qiu, JZ Zhang, B Wu, CC Xu, HH Pang… - Journal of …, 2023 - Springer
Abstract Traditional Chinese Medicines (TCMs) have been used for centuries for the
treatment and management of various diseases. However, their effective delivery to targeted …

Rapid selenoprotein activation by selenium nanoparticles to suppresses osteoclastogenesis and pathological bone loss

B Zou, Z Xiong, Y Yu, S Shi, X Li, T Chen - Advanced Materials, 2024 - Wiley Online Library
Osteoclast hyperactivation stands as a significant pathological factor contributing to the
emergence of bone disorders driven by heightened oxidative stress levels. The modulation …