Venous thromboembolism is a major cause of morbidity and mortality. The impact of the US
Surgeon General's The Surgeon General's Call to Action to Prevent Deep Vein Thrombosis …

Fibrin constitutes a major protein component of intravascular thrombi in all locations. Fibrin
formation and its functions are essential for physiological hemostasis and the pathologic …

We conducted cohort and Mendelian randomisation (MR) analyses to examine the
associations of circulating proteins with risk of venous thromboembolism (VTE) to provide …

Progress improving zinc nutrition globally is slowed by limited understanding of population
zinc status. This challenge is compounded when small differences in measurement can bias …

Quantification of individual proteins is an essential task in understanding biological
processes. For example, determination of concentrations of proteins transporting and …

The prothrombotic fibrin clot phenotype has been reported in patients with thrombotic
antiphospholipid syndrome (APS) and venous thromboembolism (VTE). Protein composition …

Background Little is known about fibrin clot composition in relation to its structure and
lysability. We investigated plasma clots protein composition and its associations with clot …

Background Residual pulmonary vascular obstruction (RPVO) is common following
pulmonary embolism (PE) but its association with fibrin clot properties is poorly understood …

Rationale: Current thrombolytic agents activate plasminogen to plasmin which triggers
fibrinolysis to dissolve thrombi. Since plasmin is a nonspecific proteolytic enzyme, all of the …

It has been reported that 476 proteins can be detected in plasma fibrin clots from patients
with venous thromboembolism. Plasma fibrin clots proteomic composition in relation to their …