Apolipoprotein (apo) B, the critical structural protein of the atherogenic lipoproteins, has two
major isoforms: apoB48 and apoB100. ApoB48 is found in chylomicrons and chylomicron …

Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Objectives: Evaluate the etiology and mechanisms underlying dyslipidemia, including
impaired lipoprotein synthesis, secretion, and clearance. Identify the risk factors and clinical …

After experiencing an acute coronary syndrome (ACS), patients are at a high risk of suffering
from recurrent ischaemic cardiovascular events, especially in the very early phase. Low …

Cardiovascular disease is the leading cause of mortality and morbidity throughout the world,
accounting for 16.7 million deaths each year. The underlying pathological process for the …

Atherosclerosis constitutes a persistent inflammatory ailment, serving as the predominant
underlying condition for coronary artery disease (CAD), peripheral artery disease (PAD) …

Background Information on the real‐world use of proprotein convertase subtilisin kexin 9
inhibitors (PCKS9is) in familial hypercholesterolemia are limited. We evaluated the pattern …

Primary hyperlipidemias include a heterogeneous set of monogenic and polygenic
conditions characterized by a strong family aggregation, severe forms of …

Background Familial hypercholesterolemia (FH) is an inherited metabolic disorder with a
high level of low-density lipoprotein cholesterol and the worse prognosis. The triglyceride …

Apolipoprotein B (ApoB) plays a crucial role in lipid and lipoprotein metabolism. The effects
of APOB locus variants on lipid profiles, metabolic syndrome, and the risk of diabetes …