Applications and limitations of mouse models for understanding human atherosclerosis

M Von Scheidt, Y Zhao, Z Kurt, C Pan, L Zeng, X Yang… - Cell metabolism, 2017 - cell.com
Most of the biological understanding of mechanisms underlying coronary artery disease
(CAD) derives from studies of mouse models. The identification of multiple CAD loci and …

The thin-cap fibroatheroma: a type of vulnerable plaque: the major precursor lesion to acute coronary syndromes

FD Kolodgie, AP Burke, A Farb, HK Gold… - Current opinion in …, 2001 - journals.lww.com
While the concept of plaquevulnerability'implies a propensity towards thrombosis, the term
vulnerable was originally intended to provide a morphologic description consistent with …

CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells

V Henn, JR Slupsky, M Gräfe, I Anagnostopoulos… - Nature, 1998 - nature.com
Abstract CD40 ligand (CD40L, CD154), a transmembrane protein structurally related to the
cytokine TNF-α, was originally identified on stimulated CD4+ T cells,,, and later on …

Caring for a relative with dementia: family caregiver burden

E Papastavrou, A Kalokerinou… - Journal of advanced …, 2007 - Wiley Online Library
Title. Caring for a relative with dementia: family caregiver burden Aim. This paper is a report
of part of a study to investigate the burden experienced by families giving care to a relative …

Acute coronary events

A Arbab-Zadeh, M Nakano, R Virmani, V Fuster - Circulation, 2012 - Am Heart Assoc
In the United States alone, 400 000 Americans die annu-ally of coronary artery disease, and
1 000 000 suffer acute coronary events, ie, myocardial infarction and sudden cardiac death …

Depression and cardiovascular disease: mechanisms of interaction

KE Joynt, DJ Whellan, CM O'connor - Biological psychiatry, 2003 - Elsevier
This article explores the relationship between depression and cardiovascular disease from a
mechanistic standpoint. Depression and cardiovascular disease are two of the most …

Cardiovascular protective effects of resveratrol

S Bradamante, L Barenghi… - Cardiovascular drug …, 2004 - Wiley Online Library
ABSTRACT Resveratrol (3, 4′, 5‐trihydroxy‐trans‐stilbene), a phytoalexin found in grape
skins, peanuts, and red wine, has been reported to have a wide range of biological and …

Healed culprit plaques in patients with acute coronary syndromes

F Fracassi, F Crea, T Sugiyama, E Yamamoto… - Journal of the American …, 2019 - jacc.org
Background: Healed plaques, morphologically characterized by a layered phenotype, are
frequently found in subjects with sudden cardiac death. However, in vivo data are lacking …

Multiple infections in carotid atherosclerotic plaques

B Chiu - American heart journal, 1999 - Elsevier
BackgroundChlamydia pneumoniae, cytomegalovirus, herpes simplex virus, and recently,
periodontal disease, have been associated with human atherosclerosis. Porphyromonas …

Effects of psychological stress and psychiatric disorders on blood coagulation and fibrinolysis: a biobehavioral pathway to coronary artery disease?

R von Känel, PJ Mills, C Fainman… - Psychosomatic …, 2001 - journals.lww.com
Objective A hypercoagulable state before overt thrombosis resulting from an imbalance
between the coagulation and fibrinolysis systems is related to cardiovascular disease …