Francisella tularensis is the causative agent of the acute disease tularemia. Due to its
extreme infectivity and ability to cause disease upon inhalation, F. tularensis has been …

Emerging and re-emerging bacterial infections are a serious threat to human and animal
health. Extracellular bacteria are free-living, while facultative intracellular bacteria replicate …

Francisella tularensis is a facultative intracellular gram-negative pathogen and the
etiological agent of the zoonotic disease tularemia. Recent advances in the field of …

Francisella tularensis has been recognized as the causative agent of tularaemia for almost a
century. Since its discovery in 1911, it has been shown to infect a wide range of hosts …

Francisella tularensis is a Gram-negative intracellular pathogen and the causative agent of
the disease tularemia. Inhalation of as few as 10 bacteria is sufficient to cause severe …

Francisella tularensis is a gram-negative pathogen that causes life-threatening infections in
humans and has potential for use as a biological weapon. The genetic basis of the F …

A key factor in the biology of Francisella spp. is lipopolysaccharide (LPS). Francisella LPS
has many unique structural properties and poorly activates proinflammatory responses due …

Studies of immune responses to Francisella have been conducted for well over 50 years.
Here, the basic parameters of innate and adaptive immune responses to Francisella are …

In recent years, studies on the intracellular pathogen Francisella tularensis have greatly
intensified, generating a wealth of new information on the interaction of this organism with …

Francisella tularensis is a highly infectious bacterium causing the zoonotic disease
tularemia. Its ability to multiply and survive in macrophages is critical for its virulence. By …