Broad‐Spectrum antiviral peptides and polymers

A Kuroki, J Tay, GH Lee… - Advanced Healthcare …, 2021 - Wiley Online Library
As the human cost of the pandemic caused by the severe acute respiratory syndrome
coronavirus 2 (SARS‐CoV‐2) is still being witnessed worldwide, the development of broad …

Batzella, Crambe and Monanchora: Highly Prolific Marine Sponge Genera Yielding Compounds with Potential Applications for Cancer and Other Therapeutic Areas

A El-Demerdash, AG Atanasov, A Bishayee… - Nutrients, 2018 - mdpi.com
Pyrroloquinoline and guanidine-derived alkaloids present distinct groups of marine
secondary metabolites with structural diversity that displayed potentialities in biological …

Tailor‐made antimicrobial/antiviral star polymer via ATRP of Cyclodextrin and guanidine‐based macromonomer

Y Pan, Y Xue, J Snow, H Xiao - Macromolecular Chemistry and …, 2015 - Wiley Online Library
Novel star‐like polymers are prepared via atom transfer radical polymerization (ATRP) of
polyhexamethylene guanidine hydrochloride (PHMG) macromonomer and acrylamide (AM) …

Investigating the structure-activity relationship of marine polycyclic batzelladine alkaloids as promising inhibitors for SARS-CoV-2 main protease (Mpro)

AM Elgohary, AA Elfiky, F Pereira… - Computers in Biology …, 2022 - Elsevier
Over a span of two years ago, since the emergence of the first case of the novel coronavirus
(SARS-CoV-2) in China, the pandemic has crossed borders causing serious health …

[PDF][PDF] Desymmetrization of meso‐2, 5‐Diallylpyrrolidinyl Ureas through Asymmetric Palladium‐Catalyzed Carboamination: Stereocontrolled Synthesis of Bicyclic …

NR Babij, JP Wolfe - 2013 - deepblue.lib.umich.edu
Catalytic asymmetric desymmetrization reactions are powerful and efficient tools for the
synthesis of chiral molecules.[1] These transformations convert simple achiral substrates into …

Analogues of Marine Guanidine Alkaloids Are in Vitro Effective against Trypanosoma cruzi and Selectively Eliminate Leishmania (L.) infantum Intracellular …

LF Martins, JT Mesquita, EG Pinto… - Journal of natural …, 2016 - ACS Publications
Synthetic analogues of marine sponge guanidine alkaloids showed in vitro antiparasitic
activity against Leishmania (L.) infantum and Trypanosoma cruzi. Guanidines 10 and 11 …

Aminoguanidine hydrazones (AGH's) as modulators of norfloxacin resistance in Staphylococcus aureus that overexpress NorA efflux pump

N Dantas, TM de Aquino, JX de Araújo-Júnior… - Chemico-biological …, 2018 - Elsevier
One of the promising fields for improving the effectiveness of antimicrobial agents is their
combination with efflux pump inhibitors (EPIs), which besides expanding the use of existing …

[HTML][HTML] Seasonal persistence of faecal indicator organisms in soil following dairy slurry application to land by surface broadcasting and shallow injection

CJ Hodgson, DM Oliver, RD Fish, NM Bulmer… - Journal of environmental …, 2016 - Elsevier
Dairy farming generates large volumes of liquid manure (slurry), which is ultimately recycled
to agricultural land as a valuable source of plant nutrients. Different methods of slurry …

Guanidine-containing antifungal agents against human-relevant fungal pathogens (2004–2022)—a review

SDP Baugh - Journal of Fungi, 2022 - mdpi.com
The guanidine moiety is typically a highly basic group, and can be found in a wide variety of
drugs, such as zanamivir (Relenza) and metformin (Fortamet), as well as in biologically …

[HTML][HTML] Search for structurally diverse heterocyclic analogs as dual-acting antimalarial and antileishmanial agents: An overview

S Dey, S Johri, M Abirami, BK Kumar… - European Journal of …, 2022 - Elsevier
Infections caused by protozoan parasites continue to be a significant cause of morbidity and
mortality across the globe, with malaria and leishmaniasis forming the fulcrum of these …