Surgical procedures are key drivers of pain development and opioid utilization globally.
Various organizations have generated guidance on postoperative pain management …

The feasibility of OFA is evident. However, there are limitations of this approach that warrant
discussion including the potential for adverse drug interactions with multimodal analgesics …

With a focus on practical acute pain management in adults in the hospital setting, this book
provides health professionals with simple and practical information to help them manage …

Highlights•The recent paradigm shift in drug development due to ketamine is described.•A
historical overview of novel and repurposed antidepressant drugs is provided.•Mechanisms …

Cancer remains the leading cause of death worldwide with close to 10 million deaths
reported annually. Due to growth of the advanced age cohort in our population, it is …

Postoperative pain is a major concern for most of the surgical patients, and an inadequate
postoperative pain control may cause a series of complications. With an effective pain …

The combination of non-steroidal anti-inflammatory drugs (NSAIDs) with non-opioid
analgesics is common in clinical practice for the treatment of acute painful conditions like …

Along with the definition of pain, the treatment of pain has evolved as we continue to
understand the natural history of pain, the different kinds of pain, and the efficacy of various …

Results As evidenced by an abundance of studies, continuous regional/neuraxial blocks are
the most effective approach for relief of severe postoperative pain. Catheters have to be …

Novel preparations allowing for the extended duration of action of local anesthetics have
many clinically relevant benefits. With regard to this, the development of liposomal …