PURPOSE: To determine the efficacy and safety of different doses of secukinumab, a fully
human monoclonal antibody for targeted interleukin-17A blockade, in patients with …

The human G-leukocyte antigen (HLA-G) molecule is a non-classical major
histocompatibility complex (MHC) class I molecule. The pertinence of HLA-G has been …

Notch pathway is a highly conserved intracellular signaling route that modulates a vast
variety of cellular processes including proliferation, differentiation, migration, cell fate and …

Objectives To identify new susceptibility loci for Behçet's disease (BD), we performed a
genome-wide association study (GWAS) using DNA pooling. Methods Two replicate pools of …

Objectives Monogenic autoinflammatory disorders (AID) and primary immunodeficiencies
can present early in life with features that may be mistaken for Behçet's disease (BD). We …

Aim. The aim of this study was to evaluate if patients with Behcet's disease who have ocular
involvement have a more severe form of this disease as compared to patients with Behcet's …

Behçet's disease (BD) is a multisystemic inflammatory disease believed to be triggered by
microbial or environmental factors on a genetic platform. Clinically, it may have an impact on …

Behçet's disease (BD) is a chronic inflammatory autoimmune disease. Although raised
levels of proinflammatory cytokines in BD have been reported, the pathogenesis is still …

Opinion statement Management of neuro-Behçet's disease can be divided into two stages:
treatment of acute attacks and prevention of relapses. Treatment of acute attacks is …

Autoimmune heart disease is a non-random condition characterised by immune system-
mediated aggression against cardiac tissue. Cardiac changes often exhibit nonspecific …