[HTML][HTML] Flavonoids targeting cancer stem cells for augmenting cancer therapeutics

A Meerson, S Khatib, J Mahajna - International Journal of Molecular …, 2021 - mdpi.com
Cancer stem cells (CSC) have been identified in several types of solid tumors. In some
cases, CSC may be the source of all the tumor cells, the cause of the tumor's resistance to …

Role of plant-derived flavonoids in cancer treatment

P Tiwari, KP Mishra - Nutrition and cancer, 2023 - Taylor & Francis
Flavonoids are polyphenolic phytochemicals, which occur naturally in plants and possess
both anti-oxidant and pro-oxidant properties. Flavonoids are gaining increasing popularity in …

MMP-2 and MMP-9 mediate cigarette smoke extract-induced epithelial-mesenchymal transition in airway epithelial cells via EGFR/Akt/GSK3β/β-catenin pathway …

H Agraval, UCS Yadav - Chemico-biological interactions, 2019 - Elsevier
Matrix metalloproteinases (MMPs) have been implicated in EMT but their role in the
regulation of cigarette smoke-induced EMT in airway epithelium is not clear. We have …

Targeting colon cancer stem cells using novel doublecortin like kinase 1 antibody functionalized folic acid conjugated hesperetin encapsulated chitosan nanoparticles

LM Lazer, Y Kesavan, R Gor, I Ramachandran… - Colloids and Surfaces B …, 2022 - Elsevier
The cancer stem cell (CSC) hypothesis is an evolving oncogenesis concept. CSCs have a
distinct ability to self-renew themselves and also give rise to a phenotypically diverse …

Acacetin induces sustained ERK1/2 activation and RIP1-dependent necroptotic death in breast cancer cells

K Kandhari, JPN Mishra, R Agarwal… - Toxicology and Applied …, 2023 - Elsevier
Acacetin (AC), a naturally occurring flavonoid has shown anticancer potential. Herein, we
studied the mechanisms of cell death and growth inhibition by AC in breast carcinoma T …

Fisetin suppresses cigarette smoke extract-induced epithelial to mesenchymal transition of airway epithelial cells through regulating COX-2/MMPs/β-catenin pathway

H Agraval, JR Sharma, N Prakash… - Chemico-biological …, 2022 - Elsevier
Cigarette smoke exposure leads to upregulation of cyclooxygenase‐2 (COX‐2), an
inducible enzyme that synthesizes prostaglandin E2 (PGE2) and promotes airway …

[PDF][PDF] Combinatory effect of hesperetin and mesenchymal stem cells on the deteriorated lipid profile, heart and kidney functions and antioxidant activity in STZ …

OM Ahmed, MA Hassan, AS Saleh - Biocell, 2020 - cdn.techscience.cn
Combinatory effect of hesperetin and mesenchymal stem cells on the deteriorated lipid profile,
heart and kidney functions and an Page 1 Combinatory effect of hesperetin and mesenchymal …

[HTML][HTML] Stage-Specific Effect of Inositol Hexaphosphate on Cancer Stem Cell Pool during Growth and Progression of Prostate Tumorigenesis in TRAMP Model

K Raina, K Kandhari, AK Jain, K Ravichandran… - Cancers, 2022 - mdpi.com
Simple Summary The stage of a tumor during cancer intervention is the most crucial factor
that determines the treatment regimen. Several bioactive natural compounds have shown …

[HTML][HTML] Functional mechanism on stem cells by tea (Camellia sinensis) bioactive compounds

Y Cheng, J Sun, H Zhao, H Guo, J Li - Food Science and Human Wellness, 2022 - Elsevier
Camellia sinensis (tea), one of the most popular commercial crops, is commonly applied in
all parts of the world. The main active ingredients of tea include polyphenols, alkaloids …

[HTML][HTML] Comparative Pre-clinical Efficacy of Chinese and Indian Cultivars of Bitter Melon (Momordica charantia) against Pancreatic Cancer

K Kandhari, S Paudel, K Raina, C Agarwal… - Journal of cancer …, 2021 - ncbi.nlm.nih.gov
Given the high rates of incidence and mortality associated with pancreatic cancer (PanC),
there is a need to develop alternative strategies to target PanC. Recent studies have …