Resistance against conventional chemotherapeutic agents is one of the main reasons for
tumor relapse and poor clinical outcomes in cancer patients. Various mechanisms are …

Cancer as one of the leading causes of human deaths has always been one of the main
health challenges in the world. Despite recent advances in therapeutic and diagnostic …

Background Cuproptosis is a new modality of cell death regulation that is currently
considered as a new cancer treatment strategy. Nevertheless, the prognostic predictive …

Background: Ferroptosis is closely related to the occurrence and development of cancer. An
increasing number of studies have induced ferroptosis as a treatment strategy for cancer …

Background Cancer, as one of the main causes of human deaths, is currently a significant
global health challenge. Since the majority of cancer-related deaths are associated with late …

Cancer is considered as one of the main causes of human deaths globally. Despite the
recent progresses in therapeutic modalities, there is still a high rate of mortality among …

Gastrointestinal (GI) cancers, as the most common human malignancies are always
considered one of the most important health challenges in the world. Late diagnosis in …

Chemotherapy is one of the main therapeutic modalities for cancer patients. Cisplatin
(CDDP), as one of the first-line drugs, is of great importance in the chemotherapy of various …

Combined chemotherapeutic treatment is the method of choice for advanced and metastatic
gastric tumors. However, resistance to chemotherapeutic agents is one of the main …

Osteosarcoma (OS) is an aggressive bone tumor that originates from mesenchymal cells. It
is considered as the eighth most frequent childhood cancer that mainly affects the tibia and …