Promising Ursolic Acid as a Novel Antituberculosis Agent: Current Progress and Challenges

DAE Pitaloka, Y Syaputri, P Nurlilasari… - Drug Design …, 2024 - Taylor & Francis
Tuberculosis (TB) stands as the second most prevalent cause of global human mortality from
infectious diseases. In 2022, the World Health Organization documented an estimated …

[HTML][HTML] Triterpenoid and steroid content of lipophilic extracts of selected medicinal plants of the Mediterranean region

L Gadouche, ASM Alsoufi, D Pacholska, A Skotarek… - Molecules, 2023 - mdpi.com
The available phytochemical characteristics of the medicinal plants and derived herbal
material often lack data concerning the content of steroids (including phytosterols) and …

[HTML][HTML] Pentacyclic Triterpenoids-Based Ionic Compounds: Synthesis, Study of Structure–Antitumor Activity Relationship, Effects on Mitochondria and Activation of …

LU Dzhemileva, RA Tuktarova, UM Dzhemilev… - Cancers, 2023 - mdpi.com
Simple Summary The search for new, effective and low-toxicity anticancer drugs is one of
the most important tasks of modern medicinal chemistry. Pentacyclic triterpenoids constitute …

[HTML][HTML] Extraction, analysis of antioxidant activities and structural characteristics of flavonoids in fruits of Diospyros lotus L.

H Wu, W Zhao, J Zhou, X Xie, X Zhong, Y Liu, L Shi - LWT, 2024 - Elsevier
Flavonoid compounds are considered important components of new sources of natural
antioxidants. This study was performed to optimize the ultrasound-assisted extraction …

[HTML][HTML] Flowers and Inflorescences of Selected Medicinal Plants as a Source of Triterpenoids and Phytosterols

P Edorh Tossa, M Belorgey, S Dashbaldan… - Plants, 2023 - mdpi.com
Steroids and triterpenoids are compounds valued for their various biological and
pharmacological properties; however, their content in medicinal and edible plants is often …

[HTML][HTML] Accessing the Medicinal Potential of Mallotus philippensis: Comprehensive Exploration of Antioxidant and Antibacterial Properties through Phytochemical …

A Ali, H Chen, H Xu, S Wang, S Yao - Separations, 2024 - mdpi.com
Plants serve as reservoirs of bioactive compounds endowed by nature, rendering them
promising subjects for investigating chemical diversity. Despite their potential, much remains …

Oleanolic acid: an antimycobacterial component of Syzygium aromaticum L. and inhibitor of efflux mediated drug resistance

Y El Ghallab, M Dakir, A Aainouss… - Natural Product …, 2024 - Taylor & Francis
Oleanolic acid (OA) was isolated from Syzygium aromaticum L. buds, and structurally
characterised using different spectroscopic techniques; MS, IR, 1H/13C-NMR and 2D NMR …

Molecular Dynamics and Docking Investigation of Flavonol Aglycones against Sulfonylurea Receptor 1 (SUR1) for Anti–diabetic Drug Design

E Oluwafisayo Akintemi, K Kuben Govender… - …, 2024 - Wiley Online Library
The effectiveness of flavonols for the treatment of certain health conditions has highlighted
their importance as an alternative to conventional therapeutic drugs. In this study, fifteen (15) …