Invasive pulmonary aspergillosis: current diagnostic methodologies and a new molecular approach

S Moura, L Cerqueira, A Almeida - European Journal of Clinical …, 2018 - Springer
The fungus Aspergillus fumigatus is the main pathogenic agent responsible for invasive
pulmonary aspergillosis. Immunocompromised patients are more likely to develop this …

Feasibility and applicability of antimicrobial stewardship in immunocompromised patients

E Robilotti, M Holubar, SK Seo… - Current opinion in …, 2017 - journals.lww.com
The application of antimicrobial stewardship principles to immunocompromised patients is
feasible, necessary, and urgent. As antimicrobial stewardship programs gain momentum …

(1→ 3)‐β‐D‐glucan testing for the detection of invasive fungal infections in immunocompromised or critically ill people

SK White, RL Schmidt, BS Walker… - Cochrane Database of …, 2020 - cochranelibrary.com
Background Invasive fungal infections (IFIs) are life‐threatening opportunistic infections that
occur in immunocompromised or critically ill people. Early detection and treatment of IFIs is …

Diagnostic value of serum galactomannan, (1,3)‐β‐d‐glucan, and Aspergillus fumigatus‐specific IgA and IgG assays for invasive pulmonary aspergillosis in non …

R Dobias, P Jaworska, H Tomaskova, M Kanova… - Mycoses, 2018 - Wiley Online Library
Detection of serum galactomannan (GM) and (1, 3)‐β‐d‐glucan (BG) is considered useful
for non‐culture diagnosis of invasive pulmonary aspergillosis (IPA) in neutropenic patients …

The lung in inborn errors of immunity: From clinical disease patterns to molecular pathogenesis

MJ Gutierrez, G Nino, D Sun… - Journal of Allergy and …, 2022 - Elsevier
In addition to being a vital organ for gas exchange, the lung is a crucial immune organ
continuously exposed to the external environment. Genetic defects that impair immune …

Invasive pulmonary aspergillosis in patients with solid tumours: risk factors and predictors of clinical outcomes

D Dandachi, R Wilson Dib, A Fernández-Cruz… - Annals of …, 2018 - Taylor & Francis
Background: The characteristics and management of invasive pulmonary aspergillosis (IPA)
in patients with hematologic malignancies are well known, but IPA in patients with solid …

Diagnostic accuracy of bronchoalveolar lavage fluid galactomannan for invasive aspergillosis

XJ Cao, YP Li, LM Xie, HL Zhang… - BioMed Research …, 2020 - Wiley Online Library
Background. The pathogenesis of invasive aspergillosis (IA) is still unknown, but its
progression is rapid and mortality rate remains high. Bronchoalveolar lavage fluid (BALF) …

Detection of invasive aspergillosis in critically ill patients with influenza: the role of plasma galactomannan

K van de Groep, DM Verboom… - American Journal of …, 2019 - atsjournals.org
Invasive pulmonary aspergillosis (IPA) is a complication of influenza infection that has been
associated with 33-67% mortality (1-3). In a recent cohort of patients with severe …

Cell wall polysaccharides from pathogenic fungi for diagnosis of fungal infectious disease

D Ahamefula Osibe, S Lei, B Wang, C Jin, W Fang - Mycoses, 2020 - Wiley Online Library
Invasive fungal diseases are associated with significant morbidity and mortality, particularly
in immunocompromised individuals. Early and accurate diagnosis is crucial for effective …

Diagnostic performance of serum galactomannan and β-D-glucan for invasive aspergillosis in suspected patients: A meta-analysis

QY Huang, PC Li, JR Yue - Medicine, 2024 - journals.lww.com
Background: Serum galactomannan (GM) and β-D-glucan (BG) are known markers of
invasive aspergillosis (IA). The aim of this meta-analysis was to evaluate the efficiency of …